Dexamethasone sodium phosphate

Base Information

• Chemical Name: Dexamethasone sodium phosphate
• CAS No.: 2392-39-4
• Deprecated CAS: 55203-24-2,2588541-26-6
• Molecular Formula: C22H30FO8P.2Na
• Molecular Weight: 516.45
• Hs Code.: 2937220000
• European Community (EC) Number: 219-243-0
• UNII: AI9376Y64P
• DSSTox Substance ID: DTXSID3047429
• Nikkaji Number: J7.881F
• Wikidata: Q27106391
• NCI Thesaurus Code: C1362
• RXCUI: 48933
• ChEMBL ID: CHEMBL2021430
• Mol file: 2392-39-4.mol

Synonyms:Decadron phosphate;dexamethasone 21-phosphate;dexamethasone 21-phosphate, (6alpha,11beta,16alpha)-isomer;dexamethasone 21-phosphate, copper (+2) salt (2:3), (11beta,16alpha)-isomer;dexamethasone 21-phosphate, disodium salt, (11beta,16alpha)-isomer;dexamethasone 21-phosphate, disodium salt, (6alpha,11beta,16alpha)-isomer;dexamethasone 21-phosphate, monosodium salt, (11beta,16alpha)-isomer;dexamethasone 21-phosphate, sodium salt, (11beta,16alpha)-isomer;dexamethasone phosphate;dexamethasone phosphate disodium salt;dexamethasone sodium phosphate;dexamethasonedisodium phosphate;Solu- Decadron;Spersadex;Spersadox

Chemical Property of Dexamethasone sodium phosphate

Chemical Property:

• Appearance/Colour: White to off white powder
• Vapor Pressure: 2.81E-15mmHg at 25°C
• Melting Point: 233-235 °C
• Refractive Index: 1.591
• Boiling Point: 669.6 °C at 760 mmHg
• Flash Point: 358.7 °C
• PSA: 156.83000
• Density: 1.32g/cm3
• LogP: 2.88910
• Storage Temp.: 2-8°C
• Solubility.: H2O: 50 mg/mL, clear, faintly yellow
• Water Solubility.: Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 3
• Exact Mass: 516.13012157
• Heavy Atom Count: 34
• Complexity: 962

Purity/Quality:

99% ^*data from raw suppliers

Dexamethasone Sodium Phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R22:; R40:; R63:
• Hazard Codes: Xn
• Statements: 22-40-63
• Safety Statements: 36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
• Isomeric SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
• Recent ClinicalTrials: Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma
• Recent EU Clinical Trials: ISATUXIMAB AND AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR RELAPSED MULTIPLE MYELOMA PATIENTS (Isabel Study)
• Uses: Dexamethasone-21-phosphate disodium salt is used in eye and ear preparations and in systemic preparations. glucocorticoid, antiinflammatory Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.
• Therapeutic Function: Glucocorticoid