Streptidine

Base Information

• Chemical Name: Streptidine
• CAS No.: 85-17-6
• Deprecated CAS: 1204293-42-4
• Molecular Formula: C8H18 N6 O4
• Molecular Weight: 262.269
• UNII: DN7462S5BR
• DSSTox Substance ID: DTXSID501018976
• Nikkaji Number: J4.910G
• Wikidata: Q27103112,Q105171519
• Metabolomics Workbench ID: 51305
• ChEMBL ID: CHEMBL3781259,CHEMBL1742957
• Mol file: 85-17-6.mol

Synonyms:1,1'-(2,4,5,6-tetrahydroxy-1,3-cyclohexylene)diguanidine;streptidine;streptidine sulfate (1:1)

Chemical Property of Streptidine

Chemical Property:

• Vapor Pressure: 3.77E-18mmHg at 25°C
• Melting Point: 225 °C (decomp)(Solv: water (7732-18-5); methanol (67-56-1))
• Boiling Point: 623.3°C at 760 mmHg
• PKA: 13.91±0.70(Predicted)
• Flash Point: 330.8°C
• PSA: 204.72000
• Density: 2.21g/cm³
• LogP: -2.47120
• XLogP3: -5.5
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 262.13895308
• Heavy Atom Count: 18
• Complexity: 322

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(C(C(C(C(C1O)O)O)N=C(N)N)O)N=C(N)N
• Isomeric SMILES: [C@H]1([C@H](C([C@H]([C@@H](C1O)N=C(N)N)O)O)O)N=C(N)N

Technology Process of Streptidine

There total 17 articles about Streptidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sulfuric acid (7664-93-9) + (1R)-N,N'-dicarbamimidoyl-O4-[3-formyl-O2-(O4-α-D-mannopyranosyl-2-methylamino-2-deoxy-α-L-glucopyranosyl)-5-deoxy-α-L-lyxofuranosyl]-streptamine (128-45-0) → D-Mannose (3458-28-4) + streptidine (85-17-6)

Guidance literature:

DOI:10.1021/ja01169a037

Reference yield:

→ streptidine (85-17-6)

Guidance literature:

With hydrogenchloride; at 120 ℃;

DOI:10.1021/ja01205a009

Reference yield:

CYANAMID (420-04-2) → streptidine (85-17-6)

Guidance literature:

With water; at 155 ℃;

DOI:10.1021/ja01191a511

upstream raw materials:

dihydrostreptomycin trihydrochloride

hydrogenchloride

water

streptomicin

Downstream raw materials:

Streptamin D

Refernces

• 1、 Holly,Mozingo,Folkers. "". . p. 3944. Retrieved 1948.