D-Streptamine

Base Information

• Chemical Name: D-Streptamine
• CAS No.: 488-52-8
• Molecular Formula: C6H14 N2 O4
• Molecular Weight: 178.188
• Mol file: 488-52-8.mol

Synonyms:1,2,3,5-Cyclohexanetetrol,4,6-diamino-; 1,3-Diamino-1,3-dideoxy-scyllo-inositol; scyllo-Inositol,1,3-diamino-1,3-dideoxy-

Chemical Property of D-Streptamine

Chemical Property:

• Vapor Pressure: 2.77E-07mmHg at 25°C
• Boiling Point: 378.6°Cat760mmHg
• Flash Point: 182.7°C
• PSA: 132.96000
• Density: 1.626g/cm³
• LogP: -2.50120

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D-Streptamine

There total 20 articles about D-Streptamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-2,4-Hydrazo-2,4-didesoxy-chiro-inosit (16703-84-7,51607-67-1,51607-70-6,51607-72-8,81602-02-0) → DL-2,4-diamino-2,4-dideoxy-chiro-inositol (488-52-8,16647-43-1,42744-70-7,81602-04-2)

Guidance literature:

With hydrogen; nickel; at 25 ℃; for 24h; under 750.06 Torr;

Reference yield:

streptidine (85-17-6) → Streptamin D (488-52-8)

Guidance literature:

With barium dihydroxide; water;

DOI:10.1021/ja01209a023

Reference yield:

cis-trisoxirane (39078-11-0) → Streptamin D (488-52-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 79 percent / 1 M aq. NH₂NH₂ / 0.58 h / 50 °C

2: 98 percent / H₂O / 20 h / 170 °C

3: 1) 5 M NaOH, 2) H₂ / 2) Raney-Ni / 1) 100 deg C, 6 h, 2) 20 deg C, 10 bar, 24 h

With sodium hydroxide; hydrogen; hydrazine hydrate; nickel; In water;

upstream raw materials:

hexaacetyl-streptamine

streptidine

1,2:4,5-Dianhydro-epi-inositol

Hexahydro-7,8,9,12-tetrahydroxy-6,10-methano-6H-pyridazino<1,2-a><1,2>diazepin-1,4-dion

Downstream raw materials:

4t,6t-bis-benzyloxycarbonylamino-cyclohexane-1r,2t,3c,5c-tetraol

4t,6t-bis-dimethylamino-cyclohexane-1r,2t,3c,5c-tetraol

N.N'-diacetyl-streptamine

Refernces

• 1、 Schubert, Juergen,Keller, Reinhold,Schwesinger, Reinhard,Prinzbach, Horst. "Polyfunctionalised Cyclohexanes from Dianhydroinositols. cis-1,3(1,4)-Inosadiamines from Benzene". . p. 2524 - 2545. Retrieved 2007/10/02.
• 2、 Schwesinger,Prinzbach. "Chemistry of cis trioxatris sigma homobenzene. A simple total synthesis of streptamine". . p. 625 - 626. Retrieved 2007/10/06.