Tectorigenin

Base Information

• Chemical Name: Tectorigenin
• CAS No.: 548-77-6
• Molecular Formula: C16H12O6
• Molecular Weight: 300.268
• Hs Code.: 2914509090
• Mol file: 548-77-6.mol

Synonyms:Tectoridin;5-18-05-00311 (Beilstein Handbook Reference);Tectorigenine;5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-4-one;4,5,7-Trihydroxy-6-methoxyisoflavone;K 251T;4H-1-Benzopyran-4-one,5,7-dihydroxy-3- (4-hydroxyphenyl)-6-methoxy-;

Chemical Property of Tectorigenin

Chemical Property:

• Melting Point: 225-226°
• Refractive Index: 1.4600 (estimate)
• Boiling Point: 601.506 °C at 760 mmHg
• PKA: 6.49±0.20(Predicted)
• Flash Point: 230.135 °C
• PSA: 100.13000
• Density: 1.512 g/cm³
• LogP: 2.58540
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tectorigenin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Tectorigenin is identified as an α-glucosidase inhibitors. Potent lactate dehydrogenase (LDH) inhibitor.

Technology Process of Tectorigenin

There total 24 articles about Tectorigenin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

tectorigenin 7-O-[β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside] → tectorigenin (548-77-6)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 2h;

DOI:10.1016/S0031-9422(01)00195-9

Reference yield: 40.0%

4'-methoxytectorigenin (2345-17-7) → tectorigenin (548-77-6)

Guidance literature:

With boron tribromide; In dichloromethane; at -70 ℃; for 3h;

Reference yield:

tectoridine → tectorigenin (548-77-6)

Guidance literature:

With Bacteriodes spercoris HJ-15; In various solvent(s); at 37 ℃; for 24h;

DOI:10.1016/j.ejphar.2005.06.043

upstream raw materials:

3-(4-amino-phenyl)-5,7-dihydroxy-6-methoxy-chromen-4-one

4'-methoxytectorigenin

tectorigenin 4'-O-β-D-glucoside

7-Hydroxy-3-(4-hydroxy-phenyl)-5-isopropoxy-6-methoxy-chromen-4-one

Downstream raw materials:

6-Hydroxygenistein

4',5,7-trihydroxy-8-methoxyisoflavone

4H-benzopyran-4-one-5-hydroxy-6,7-dimethoxy-3-(4-methoxyphenyl)

1-(2',6'-dihydroxy-3',4'-dimethoxyphenyl)-2-(4''-methoxyphenyl)ethanone

Refernces

• 1、 Shawl, Abdul S.,Kumar, Tej. "ISOFLAVONOIDS FROM IRIS CROCEA". . p. 1399 - 1402. Retrieved 1992.
• 2、 Gupta, Bodhendu B.,Bhattacharyya, Anjan,Mitra, Santi R,Adityachaudhury, Narayan. "ISOAURMILLONE, AN ISOFLAVONE FROM THE PODS OF MILLETIA AURICULATA". . p. 1306 - 1307. Retrieved 1983.
• 3、 Bai, Xue,Xie, Yuanyuan,Liu, Jia,Qu, Jialin,Kano, Yoshihiro,Yuan, Dan. "Isolation and identification of urinary metabolites of kakkalide in rats". experimental part. p. 281 - 286. Retrieved 2010/11/17.