2-PHENYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER

Base Information

• Chemical Name: 2-PHENYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
• CAS No.: 97-71-2
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.242
• Hs Code.: 2916399090
• Mol file: 97-71-2.mol

Synonyms:

Chemical Property of 2-PHENYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 0.00851mmHg at 25°C
• Melting Point: 35 - 37 °C
• Boiling Point: 266.7°Cat760mmHg
• Flash Point: 106.9°C
• PSA: 26.30000
• Density: 1.108g/cm³
• LogP: 2.35320

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-phenylcyclopropanecarboxylate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-PHENYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER

There total 185 articles about 2-PHENYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + diazoacetic acid ethyl ester (623-73-4) → ethyl 2-phenylcyclopropylcarboxylate (946-38-3,946-39-4,34702-96-0,34702-97-1,34703-00-9,34716-60-4,63038-62-0,63038-63-1,97-71-2) + diethyl Fumarate (623-91-6) + Diethyl maleate (141-05-9)

Guidance literature:

hexarhodium hexadecacarbonyl; at 25 ℃; for 7h;

DOI:10.1016/S0040-4039(01)90438-1

Reference yield: 84.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + diazoacetic acid ethyl ester (623-73-4) → ethyl (S,S)-2-phenylcyclopropane-1-carboxylate (97-71-2,946-38-3,946-39-4,34702-96-0,34702-97-1,34703-00-9,34716-60-4,63038-62-0,63038-63-1) + (1R,2R)-2-phenyl-cyclopropanecarboxylic acid ethyl ester (97-71-2,946-38-3,946-39-4,34702-96-0,34702-97-1,34703-00-9,34716-60-4,63038-62-0,63038-63-1)

Guidance literature:

With Co(carBPI)(OAc); In toluene; for 16h; enantioselective reaction; Inert atmosphere;

DOI:10.1002/anie.200801150

Reference yield: 84.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + diazoacetic acid ethyl ester (623-73-4) → ethyl (S,S)-2-phenylcyclopropane-1-carboxylate (97-71-2,946-38-3,946-39-4,34702-96-0,34702-97-1,34703-00-9,34716-60-4,63038-62-0,63038-63-1) + (1R,2R)-2-phenyl-cyclopropanecarboxylic acid ethyl ester (97-71-2,946-38-3,946-39-4,34702-96-0,34702-97-1,34703-00-9,34716-60-4,63038-62-0,63038-63-1)

Guidance literature:

With Co(carBPI)(OAc); In toluene; for 16h; enantioselective reaction; Inert atmosphere;

DOI:10.1002/anie.200801150

upstream raw materials:

styrene

diazoacetic acid ethyl ester

(1R,2S)-ethyl 2-phenylcyclopropane-1-carboxylate

ethanol

Downstream raw materials:

2-phenyl-cyclopropanecarboxylic acid

(2-phenylcyclopropyl)methanol

(1S*,2R*)-2-phenylcyclopropane-1-carboxylic acid

trans-2-phenylcyclopropane-1-carboxylic acid

Refernces

• 1、 Cheng, Shun-Cheung,Cheung, Wai-Man,Chong, Man-Chun,Ko, Chi-Chiu,Leung, Wa-Hung,Sung, Herman H.-Y.,Williams, Ian D.. "Synthesis, structure and reactivity of iridium complexes containing a bis-cyclometalated tridentate C^N^C ligand". . p. 8512 - 8523. Retrieved 2021/06/28.
• 2、 Aldin, Mohammed Zain,Delaude, Lionel,Zaragoza, Guillermo. "Synthesis of ruthenium–dithiocarbamate chelates bearing diphosphine ligands and their use as latent initiators for atom transfer radical additions". supporting information. . Retrieved 2021/08/03.