Cacodylic acid

Base Information

• Chemical Name: Cacodylic acid
• CAS No.: 75-60-5
• Deprecated CAS: 11126-73-1,58114-73-1,8073-10-7,58114-73-1
• Molecular Formula: C2H7 As O2
• Molecular Weight: 137.998
• Hs Code.: 29310099
• European Community (EC) Number: 200-883-4
• NSC Number: 71159,103115
• UN Number: 1572
• UNII: AJ2HL7EU8K
• DSSTox Substance ID: DTXSID7020508
• Nikkaji Number: J2.395G
• Wikipedia: Cacodylic_acid
• Wikidata: Q420680
• NCI Thesaurus Code: C80595
• Metabolomics Workbench ID: 147540
• ChEMBL ID: CHEMBL1231644
• Mol file: 75-60-5.mol

Synonyms:Acid, Cacodylic;Acid, Dimethylarsinic;Cacodylate;Cacodylic Acid;Dimethylarsinate;Dimethylarsinic Acid

Chemical Property of Cacodylic acid

Chemical Property:

• Appearance/Colour: colorless or white crystalline powder
• Vapor Pressure: 0.00288mmHg at 25°C
• Melting Point: 195-198 °C
• Boiling Point: 253.1 °C at 760 mmHg
• PKA: 1.57(at 25℃)
• Flash Point: 109.4 °C
• PSA: 37.30000
• Density: >1.1(20oC)
• LogP: 0.11100
• Storage Temp.: Store at RT.
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble in water (50 mg/ml), water (2000 at 25°C), alcohols, and acetic acid. Insoluble in ether.
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 137.966199
• Heavy Atom Count: 5
• Complexity: 62
• Transport DOT Label: Poison

Purity/Quality:

98%, ^*data from raw suppliers

Cacodylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): TN
• Hazard Codes: T,N
• Statements: 23/25-50/53
• Safety Statements: 20/21-28-45-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Arsenic Compounds, Organic
• Canonical SMILES: C[As](=O)(C)O
• Uses: Cacodylic acid is used for dermatologic treatment in cronic eczema, anemia and as a tonic. antieczema, dermatologic, herbicide A useful arsenic acid for proteomics research. It a good substitute for phosphate in applications to avoid phosphates. Cacodylic Acid is useful for some DNA applications and is also popular in microscopy.

Technology Process of Cacodylic acid

There total 31 articles about Cacodylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylarsine (593-88-4) → trimethylarsine oxide (4964-14-1) + Dimethylarsinic acid (75-60-5)

Guidance literature:

With air;

DOI:10.1039/jr9350000396

Reference yield:

trimethylarsine (593-88-4) → trimethylarsine oxide (4964-14-1) + Dimethylarsinic acid (75-60-5)

Guidance literature:

DOI:10.1039/jr9350000396

Reference yield:

bis-{dimethylarsenic}-oxide (503-80-0) + dihydrogen peroxide (7722-84-1) → trimethylarsine (593-88-4) + methylarsine oxide (593-58-8) + Dimethylarsinic acid (75-60-5)

Guidance literature:

Produkt 5: Trimethylarsinoxyd; Produkt 6: Methylarsinsaeure;

upstream raw materials:

trimethylarsine

Dimethylchloroarsine

tetramethyldiarsine

bis-{dimethylarsenic}-oxide

Downstream raw materials:

cysteinyldimethylthioarsenite

trichloro-dimethyl-arsorane

methylphosphate

methylarsine oxide

Refernces

• 1、 Vansant et al.. "". . p. 69. Retrieved 1974.
• 2、 -. "COMPOSITION FOR ALKYLATION, AND METHOD FOR DETOXIFICATION OF TOXIC COMPOUND USING THE COMPOSITION". Page/Page column 17-18. . Retrieved 2009/06/27.