Dichloromethane-d2

Base Information

• Chemical Name: Dichloromethane-d2
• CAS No.: 1665-00-5
• Molecular Formula: CCl2D2
• Molecular Weight: 86.917
• Hs Code.: 28459000
• European Community (EC) Number: 216-776-0
• DSSTox Substance ID: DTXSID80937204
• Nikkaji Number: J150.032E
• Wikipedia: Deuterated_dichloromethane
• Wikidata: Q1101325
• Mol file: 1665-00-5.mol

Synonyms:Dichloromethane-d2;1665-00-5;Methylene chloride-D2;dichloro(dideuterio)methane;Dichloro(2H2)methane;Dideuteromethylenechloride;Methane-d2, dichloro- (6CI,7CI,8CI,9CI);Methane-d2, dichloro-;CD2Cl2;Dichloromethane, deuterated;EINECS 216-776-0;Dideuteromethylene Chloride;MFCD00000882;Dichloromethane-d2, 99.9 atom % D;Dichloromethane-d2, "100%", 99.96 atom % D;Deuterated dichloromethane;Dichloromethane D2;Dichlorodideuteriomethane;CCl2D2;Methane-D2-, dichloro-;C-Cl2-D2;CD2C12;DTXSID80937204;CHEBI:193042;Methylene Chloride D2 >99.6%;AKOS015904236;Dichloromethane-d2, 99.5 atom % D;CS-T-33750;Dichloromethane-d2, 100.0 atom % D;AS-75499;D3529;D3569;Methane-d2, dichloro-(6CI,7CI,8CI,9CI);Dichloromethane D2 100 microg/mL in Methanol;D90197;Methylene chloride-D2 (D, 99.8%) reagent grade;J-010289;Q1101325;Dichloromethane-d2, 99.5 atom % D, contains 1 % (v/v) TMS;Dichloromethane-d2, 99.5 atom % D, contains 0.1 % (v/v) TMS;Dichloromethane-d2, 99.9 atom % D, contains 0.1 % (v/v) TMS;Dichloromethane-d2, >=99.5 atom % D, contains 0.03 % (v/v) TMS

Chemical Property of Dichloromethane-d2

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 25.72 psi ( 55 °C)
• Melting Point: 97 °C
• Refractive Index: n20/D 1.4217(lit.)
• Boiling Point: 39.6 °C at 760 mmHg
• PSA: 0.00000
• Density: 1.282 g/cm³
• LogP: 1.42150
• Storage Temp.: Store below +30°C.
• Sensitive.: Moisture Sensitive
• Solubility.: Miscible with alcohol, ether and dimethyl formamide.
• Water Solubility.: Insoluble in water. Soluble in acetone, chloroform, tetrachloromethane, dimethylfomrarnide.
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 85.9659089
• Heavy Atom Count: 3
• Complexity: 2.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methylene Chloride-d2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 40-67-36/37/38
• Safety Statements: 23-24/25-36/37-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Chlorinated Aliphatics
• Canonical SMILES: C(Cl)Cl
• Isomeric SMILES: [2H]C([2H])(Cl)Cl
• Uses: DICHLOROMETHANE-D2 is a labelled Methylene Chloride used in organic chemical reactions as a general solvent. NMR solvent Dichloromethane-d2 may be used to analyze the three-dimensional structure of (9S,11S)-11-amino-9-deoxo-11,12-deoxy-9,12-epoxyerythromycin by proton NMR derived constrained molecular mechanics.

Technology Process of Dichloromethane-d2

There total 1 articles about Dichloromethane-d2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloroform-d1 (865-49-6) + deuteroacetic acid (758-12-3) → dichloromethane-d2 (1665-00-5)

Guidance literature:

With zinc;

DOI:10.1063/1.1700773

Reference yield: 95.0%

dichloromethane-d2 (1665-00-5) + diethylamine (109-89-7) + phenylacetylene (536-74-3) → N,N-diethyl-3-phenyl-2-deuteriopropyn-1-amine (1268631-99-7)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(l) chloride; In acetonitrile; at 60 ℃; for 14h; Inert atmosphere;

DOI:10.1002/adsc.201000691

Reference yield: 80.0%

dichloromethane-d2 (1665-00-5) + 4-(3-phenyl-propionyl)-morpholine (17077-46-2) → N-[1-(2-phenylethyl)-2,2,3,3-tetradeuteriocyclopropyl]morpholine

Guidance literature:

With titanium tetrachloride; magnesium; In tetrahydrofuran; 1,2-dichloro-ethane; at 0 - 25 ℃; for 10h;

DOI:10.1021/ol060438p

upstream raw materials:

chloroform-d1

deuteroacetic acid

Downstream raw materials:

6-monodeuteroindolizine

1-d-pyrrolo-3-azabenzvalene

naphthalene

diiodomethane-d2