5-Methoxy-3,4-methylenedioxyamphetamine

Base Information

• Chemical Name: 5-Methoxy-3,4-methylenedioxyamphetamine
• CAS No.: 13674-05-0
• Deprecated CAS: 64638-02-4
• Molecular Formula: C11H15 N O3
• Molecular Weight: 209.24
• UNII: RG7FY73ZAA
• DSSTox Substance ID: DTXSID50860757
• Nikkaji Number: J50.063A
• Wikipedia: MMDA_(drug)
• Wikidata: Q4030702
• Metabolomics Workbench ID: 146100
• ChEMBL ID: CHEMBL126506
• Mol file: 13674-05-0.mol

Synonyms:3-methoxy-4,5-methylenedioxyamphetamine;3-methoxy-4,5-methylenedioxyphenylisopropylamine;MMDA;MMDA hydrochloride;MMDA hydrochloride, (+-)-isomer;MMDA, (+-)-isomer;MMDA, (R)-isomer

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 5-Methoxy-3,4-methylenedioxyamphetamine

Chemical Property:

• Vapor Pressure: 0.000393mmHg at 25°C
• Boiling Point: 317.1°Cat760mmHg
• PKA: 9.66±0.10(Predicted)
• Flash Point: 154.1°C
• PSA: 53.71000
• Density: 1.175g/cm³
• LogP: 2.01390
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 209.10519334
• Heavy Atom Count: 15
• Complexity: 212

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC2=C(C(=C1)OC)OCO2)N

Technology Process of 5-Methoxy-3,4-methylenedioxyamphetamine

There total 4 articles about 5-Methoxy-3,4-methylenedioxyamphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-methoxy-6-(2-nitro-propenyl)-benzo[1,3]dioxole (97383-34-1) → 3-methoxy-4,5-methylenedioxyamphetamine (13674-05-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; toluene; for 4h; Heating / reflux;

Reference yield: 63.63%

2-bromo-1-(3-methoxy-4,5-methylenedioxyphenyl)propane (157426-98-7) → 3-methoxy-4,5-methylenedioxyamphetamine (13674-05-0)

Guidance literature:

With ammonium hydroxide; In methanol; at 20 ℃;

DOI:10.4014/jmb.1908.08009

Reference yield: 15.3%

myristicin (607-91-0) → 3-methoxy-4,5-methylenedioxyamphetamine (13674-05-0)

Guidance literature:

With ammonium hydroxide; Spirulina platensis phenylalanine ammonia-lyase; In acetone; at 37 ℃; for 1h; pH=8; Reagent/catalyst; Enzymatic reaction;

DOI:10.4014/jmb.1908.08009

upstream raw materials:

4-methoxy-6-(2-nitro-propenyl)-benzo[1,3]dioxole

myristicin

2-bromo-1-(3-methoxy-4,5-methylenedioxyphenyl)propane

Refernces

• 1、 -. "ECSTASY HAPTENS AND IMMUNOGENS". Page/Page column 55. . Retrieved 2010/02/12.