N,N-Dibutylformamide

Base Information

• Chemical Name: N,N-Dibutylformamide
• CAS No.: 761-65-9
• Molecular Formula: C9H19 N O
• Molecular Weight: 157.256
• Hs Code.: 2924199090
• European Community (EC) Number: 212-090-0
• NSC Number: 404525
• UNII: 4315805S5N
• DSSTox Substance ID: DTXSID3022114
• Nikkaji Number: J49.547F
• Wikidata: Q27258593
• Mol file: 761-65-9.mol

Synonyms:N,N-DIBUTYLFORMAMIDE;761-65-9;Dibutylformamide;Formamide, N,N-dibutyl-;N,N-Di-n-butylformamide;Formamide, N,N-di-n-butyl-;Dibutylamid kyseliny mravenci;EINECS 212-090-0;Dibutylamid kyseliny mravenci [Czech];NSC 404525;BRN 0636100;AI3-18810;UNII-4315805S5N;NSC-404525;4315805S5N;EC 212-090-0;4-04-00-00565 (Beilstein Handbook Reference);formamide, dibutyl-;Formamide,N-dibutyl-;n,n-dibutyl-formamide;Formamide,N-di-n-butyl-;n,n-di(n-butyl)formamide;ETHYLMERCURICCHLORIDE;SCHEMBL26772;N,N-Dibutylformamide, 99%;WLN: VHN4&4;DTXSID3022114;AMY3064;BCP29821;DI(N-BUTYL)FORAMIDE, N,N-;MFCD00003289;NSC404525;AKOS009157162;LS-69455;CS-0187560;D2147;FT-0629573;E78231;A849002;W-104375;Q27258593;F0001-1929

Chemical Property of N,N-Dibutylformamide

Chemical Property:

• Appearance/Colour: Colorless liquid.
• Vapor Pressure: <1 mm Hg ( 20 °C)
• Melting Point: <-30°C
• Refractive Index: n20/D 1.44(lit.)
• Boiling Point: 120 °C15 mm Hg(lit.)
• PKA: -0.44±0.70(Predicted)
• Flash Point: 100 ºC
• PSA: 20.31000
• Density: 0.864
• LogP: 2.68090
• Storage Temp.: 2-8°C
• Water Solubility.: Insoluble in water.
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 157.146664230
• Heavy Atom Count: 11
• Complexity: 85.6

Purity/Quality:

99.9% ^*data from raw suppliers

N,N-Dibutylformamide >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 37-43-36/37/38
• Safety Statements: 36/37-37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Amides (
• Canonical SMILES: CCCCN(CCCC)C=O
• Uses: N,N-dibutylformamide is a pollutant sourcing from aerosols and or exhaust gases in Los Angeles.

Technology Process of N,N-Dibutylformamide

There total 57 articles about N,N-Dibutylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

tributyl-amine (102-82-9) → N,N-dibutylformamide (761-65-9)

Guidance literature:

With manganese(III) oxide; oxygen; In tetrahydrofuran; at 140 ℃; for 24h; under 3000.3 Torr; Reagent/catalyst; Pressure; Solvent; Temperature; Autoclave; Green chemistry;

Reference yield: 98.0%

dihydroxyacetone (96-26-4,26776-70-5) + dibutylamine (111-92-2) → N,N-dibutylformamide (761-65-9)

Guidance literature:

With Cu/Al₂O₃; dihydrogen peroxide; In water; at 25 ℃; for 24h; Green chemistry;

Reference yield: 95.0%

formic acid (64-18-6) + dibutylamine (111-92-2) → N,N-dibutylformamide (761-65-9)

Guidance literature:

With aminoproplylated mesoporous SBA-15 silica; at 40 ℃; for 0.0833333h; chemoselective reaction; Neat (no solvent);

DOI:10.1135/cccc2011131

upstream raw materials:

formic acid

dibutylamine

hydrogen cyanide

chloroform

Downstream raw materials:

N-methyldibutylamine

N-nitrosodibutylamine

N-nitrodibutylamine

2-butyl-6-(butylamino)-1H-benz(de)isoquinoline-1,3(2H)-dione

Refernces

• 1、 Yang, Jie,Wang, Liujie,Sun, Aili,Zhiani, Rahele. "Mesoporous Sn(IV) Doping DFNS Supported BaMnO3 Nanoparticles for Formylation of Amines Using Carbon Dioxide". . p. 573 - 581. Retrieved 2020/07/27.
• 2、 Ren, Qinggang,Chen, Yaju,Qiu, Yongjian,Tao, Leiming,Ji, Hongbing. "Ionization of Porous Hypercrosslinked Polymers for Catalyzing Room-Temperature CO2 Reduction via Formamides Synthesis". . p. 2919 - 2927. Retrieved 2021/02/01.