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Technology Process of Riulcfstkrdhbx-uhfffaoysa-N

Riulcfstkrdhbx-uhfffaoysa-N

Base Information Edit
  • Chemical Name:Riulcfstkrdhbx-uhfffaoysa-N
  • CAS No.:440-17-5
  • Molecular Formula:C21H26Cl2F3N3S
  • Molecular Weight:480.425
  • Hs Code.:29343000
  • Mol file:440-17-5.mol
Riulcfstkrdhbx-uhfffaoysa-N

Synonyms:NSC17474;RIULCFSTKRDHBX-UHFFFAOYSA-N;10-[3-(4-methylpiperazin-1-ium-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;chloride

Suppliers and Price of Riulcfstkrdhbx-uhfffaoysa-N
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Trifluoperazine dihydrochloride
  • 1g
  • $ 299.00
  • TRC
  • Trifluoperazine dihydrochloride
  • 50mg
  • $ 65.00
  • TCI Chemical
  • Trifluoperazine Dihydrochloride >98.0%(HPLC)(T)
  • 25g
  • $ 309.00
  • TCI Chemical
  • Trifluoperazine Dihydrochloride >98.0%(HPLC)(T)
  • 5g
  • $ 89.00
  • Sigma-Aldrich
  • Trifluoperazine dihydrochloride ≥99%, powder
  • 5g
  • $ 82.60
  • Sigma-Aldrich
  • Trifluoperazine hydrochloride meets USP testing specifications
  • 5g
  • $ 108.00
  • Sigma-Aldrich
  • Trifluoperazine dihydrochloride ≥99%, powder
  • 10g
  • $ 155.00
  • Sigma-Aldrich
  • Trifluoperazine dihydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • 1 mL
  • $ 135.00
  • Sigma-Aldrich
  • Trifluoperazine dihydrochloride solution
  • 117-1ml
  • $ 131.00
  • Sigma-Aldrich
  • Trifluoperazine hydrochloride European Pharmacopoeia (EP) Reference Standard
  • $ 190.00
Total 100 raw suppliers
Chemical Property of Riulcfstkrdhbx-uhfffaoysa-N Edit
Chemical Property:
  • Appearance/Colour:Cream fine powder 
  • Vapor Pressure:2.32E-10mmHg at 25°C 
  • Melting Point:243 °C (dec.)(lit.) 
  • Boiling Point:506 °C at 760 mmHg 
  • PKA:pK1 3.9, pK2 8.1(at 25℃) 
  • Flash Point:259.8 °C 
  • PSA：35.02000 
  • LogP:6.49040 
  • Storage Temp.:2-8°C 
  • Solubility.:ethanol: soluble5mg/mL 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:7
  • Rotatable Bond Count:4
  • Exact Mass:443.1409812
  • Heavy Atom Count:29
  • Complexity:510
Purity/Quality:

99% *data from raw suppliers

Trifluoperazine dihydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn 
  • Hazard Codes:Xn 
  • Statements: 22 
  • Safety Statements: 36 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CN1CC[NH+](CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.[Cl-]
  • Description Trifluoperazine (TFP) is a phenothiazine compound with anti-adrenergic and anti-dopaminergic actions typical of antipsychotic agents. It antagonizes adrenergic receptors, with selectivity for α1 over the α2 subtypes (Kis = 24, 653, 163, and 391 nM for α1A, α2A, α2B, and α2C, respectively). TFP binds with much higher affinity to the dopamine D2-like receptor (Kd = 0.96 nM) compared to the dopamine D4-like and the serotonin 5-HT2A receptors (Kds = 44 and 135 nM, respectively). Furthermore, TFP antagonizes calmodulin (CaM) and alters the calcium-binding properties of calsequestrin (CSQ). TFP has been shown to activate type-2 ryanodine receptors independently of its CaM and CSQ activity.
  • Uses Trifluoperazine dihydrochloride has been used as a calmodulin kinase antagonist in cultured Aplysia californica neurons. Trifluoperazine dihydrochloride has also been used as a PMCA inhibitor in mouse duodenal tissues to block the transcellular active calcium flux. Antipsychotic
  • Therapeutic Function Tranquilizer

Total 8 Pictures about this product

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