2,3,5-Triphenyltetrazolium chloride

Base Information

• Chemical Name: 2,3,5-Triphenyltetrazolium chloride
• CAS No.: 298-96-4
• Deprecated CAS: 80949-00-4,52230-05-4
• Molecular Formula: C19H15N4Cl
• Molecular Weight: 334.808
• Hs Code.: 29339900
• European Community (EC) Number: 206-071-6
• NSC Number: 5053
• UNII: D25727K0RB
• DSSTox Substance ID: DTXSID30889340
• Wikipedia: Tetrazolium_chloride
• Wikidata: Q415248
• Metabolomics Workbench ID: 67576
• ChEMBL ID: CHEMBL401540
• Mol file: 298-96-4.mol

Synonyms:2,3,5-triphenyltetrazolium chloride;triphenyltetrazolium;triphenyltetrazolium bromide;triphenyltetrazolium chloride

Chemical Property of 2,3,5-Triphenyltetrazolium chloride

Chemical Property:

• Appearance/Colour: white powder
• Vapor Pressure: 0.0615mmHg at 25°C
• Melting Point: 250 °C(lit.)
• Refractive Index: 1.6110 (estimate)
• Boiling Point: >360
• Flash Point: 91.7oC
• PSA: 34.59000
• Density: 1.1704 (rough estimate)
• LogP: 0.21500
• Storage Temp.: 2-8°C
• Sensitive.: Light Sensitive & Hygroscopic
• Solubility.: H2O: may be clear to slightly hazy
• Water Solubility.: Soluble in water, ethanol and acetone. Insoluble in ether.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 334.0985242
• Heavy Atom Count: 24
• Complexity: 330

Purity/Quality:

99% ^*data from raw suppliers

2,3,5-Triphenyltetrazolium Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Other Dyes
• Canonical SMILES: C1=CC=C(C=C1)C2=NN([N+](=N2)C3=CC=CC=C3)C4=CC=CC=C4.[Cl-]
• Recent ClinicalTrials: Comparison of Electrical Pudendal Nerve Stimulation and Tolterodine Tartrate for Urgency-Frequency Syndrome in Women
• Uses: 2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies. 2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia In analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases.

Technology Process of 2,3,5-Triphenyltetrazolium chloride

There total 9 articles about 2,3,5-Triphenyltetrazolium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,3,5-triphenylformazan (531-52-2) → triphenyltetrazolium chloride (298-96-4)

Guidance literature:

With thallium(III) acetate; In acetic acid;

Reference yield: 88.0%

1,3,5-triphenylformazan (49624-20-6) → triphenyltetrazolium chloride (298-96-4)

Guidance literature:

With N-chlorobenzotriazole; In benzene; for 0.25h; Heating;

Reference yield:

tert-butylhypochlorite (507-40-4) + 1,3,5-triphenylformazan (531-52-2) → triphenyltetrazolium chloride (298-96-4)

Guidance literature:

With potassium hydroxide; chloroform;

DOI:10.1021/ja01635a070

upstream raw materials:

N-chloro-succinimide

1,3,5-triphenylformazan

N-chlorophthalimide

tert-butylhypochlorite

Downstream raw materials:

2,3,5-triphenyl-tetrazolium; hydroxide

2-phenyl-benzo[c]tetrazolo[2,3-a]cinnolinylium; chloride

2,3,5-triphenyl-tetrazolium; triiodide

N′-phenylbenzimidohydrazide

Refernces

• 1、 Benson et al.. "-". . p. 1695. Retrieved 1954.
• 2、 Frolova,Vatsadze,Stash,Rakhimov,Zyk. "Oxidation of 3-(3-or 4-pyridyl)-1,5-diphenylformazans in tetrazolium trichlorometallates: Structural and electrochemical investigation". . p. 1444 - 1456. Retrieved 2008/09/21.
• 3、 -. "Imidazo heterocyclic compounds". . . Retrieved 2011/07/06.