4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester

Base Information

• Chemical Name: 4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester
• CAS No.: 299205-79-1
• Molecular Formula: C₁₃H₂₀O₅S
• Molecular Weight: 288.365
• Mol file: 299205-79-1.mol

Synonyms:4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester

Chemical Property of 4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester

There total 2 articles about 4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Dimethoxymethane (109-87-5) + 4-methylbenzenesulfonic acid, 4-hydroxybutyl ester (6972-09-4) → 4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester (299205-79-1)

Guidance literature:

With phosphorus pentoxide; In various solvent(s); for 0.5h;

DOI:10.1021/jo0003044

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → 4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester (299205-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / pyridine / DMAP / CH₂Cl₂ / 3.67 h / -5 - 0 °C

2: 92 percent / P₂O₅ / various solvent(s) / 0.5 h

With pyridine; phosphorus pentoxide; dmap; In dichloromethane; 1: Tosylation / 2: Substitution;

DOI:10.1021/jo0003044

Reference yield: 60.0%

4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester (299205-79-1) + 1,1'-(1,4-butanediyl)bis[5-bromo-2-methoxybenzene] (299205-61-1)

Guidance literature:

1,1'-(1,4-butanediyl)bis[5-bromo-2-methoxybenzene]; With magnesium; In tetrahydrofuran; Heating;

4-methylbenzenesulfonic acid, 4-(methoxymethoxy)butyl ester; With copper(I) bromide dimethylsulfide complex; lithium thiophenoxide; lithium bromide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; Further stages.; Heating;

DOI:10.1021/jo0003044

upstream raw materials:

Dimethoxymethane

4-methylbenzenesulfonic acid, 4-hydroxybutyl ester

p-toluenesulfonyl chloride

Refernces