Oxyclozanide

Base Information

• Chemical Name: Oxyclozanide
• CAS No.: 2277-92-1
• Molecular Formula: C13H6Cl5NO3
• Molecular Weight: 401.461
• Hs Code.: DERIVATION
• European Community (EC) Number: 218-904-0,809-018-0
• UNII: 1QS9G4876X
• DSSTox Substance ID: DTXSID50177312
• Nikkaji Number: J7.385G
• Wikipedia: Oxyclozanide
• Wikidata: Q7115903
• NCI Thesaurus Code: C66279
• ChEMBL ID: CHEMBL2105450
• Mol file: 2277-92-1.mol

Synonyms:Oxiclozanidum;Oxyclozanide;Zanil

Chemical Property of Oxyclozanide

Chemical Property:

• Appearance/Colour: white to yellowish powder
• Vapor Pressure: 1.43E-08mmHg at 25°C
• Melting Point: 77-81 °C
• Refractive Index: 1.722
• Boiling Point: 446 °C at 760 mmHg
• PKA: 5.07±0.50(Predicted)
• Flash Point: 223.5 °C
• PSA: 69.56000
• Density: 1.784 g/cm³
• LogP: 5.69010
• Storage Temp.: 0-6°C
• Water Solubility.: 29mg/L(25 oC)
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 400.876081
• Heavy Atom Count: 22
• Complexity: 415

Purity/Quality:

99% ^*data from raw suppliers

Oxyclozanide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N,Xi
• Hazard Codes: Xn;N,N,Xn,Xi
• Statements: 22-50/53-36/37/38
• Safety Statements: 60-61-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1NC(=O)C2=C(C(=CC(=C2Cl)Cl)Cl)O)O)Cl)Cl
• Uses: Anthelmintic

Technology Process of Oxyclozanide

There total 1 articles about Oxyclozanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ oxyclozanide (2277-92-1)

Guidance literature:

entspr. Salicyloylchlorid, entspr. o-Aminophenol;

Reference yield:

oxyclozanide (2277-92-1) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → oxyclozanidebenzene hemisolvate

Guidance literature:

at 20 ℃; for 168h;

DOI:10.1107/S2053229617015923

Reference yield:

para-xylene (106-42-3) + oxyclozanide (2277-92-1) → oxyclozanide xylene hemisolvate

Guidance literature:

at 20 ℃; for 168h;

DOI:10.1107/S2053229617015923