Technology Process of alpha-Pentyl-3-(2-quinolinylmethoxy)benzenemethanol
There total 9 articles about alpha-Pentyl-3-(2-quinolinylmethoxy)benzenemethanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 75 ℃;
for 20h;
DOI:10.1021/jo00064a043
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) lithium diisopropylamide / 1) THF, -78 deg C, 1 h, 2) THF, -78 deg C, 0.3 h
2: 80 percent / p-toluenesulfonic acid monohydrate, 3 Angstroem molecular sieves / toluene / 22 h / 40 °C
3: 98 percent / H2 / 10percent Pd-C / ethanol / 1 h / 25 °C / 760 Torr
4: 86 percent / K2CO3 / dimethylformamide / 20 h / 75 °C
With
3 A molecular sieve; hydrogen; potassium carbonate; toluene-4-sulfonic acid; lithium diisopropyl amide;
palladium on activated charcoal;
In
ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00064a043
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 98 percent / H2 / 10percent Pd-C / ethanol / 1 h / 25 °C / 760 Torr
2: 86 percent / K2CO3 / dimethylformamide / 20 h / 75 °C
With
hydrogen; potassium carbonate;
palladium on activated charcoal;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo00064a043
Xi
