Technology Process of 3,6-dimethoxy-4,5-dichlorocatechol
There total 7 articles about 3,6-dimethoxy-4,5-dichlorocatechol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 88 percent / conc. aq. HCl / 14 h
2: 1.) n-BuLi, 2.) N,N-dimethylformamide / 1.) THF, hexane, RT, 2 h, 2.) THF,hexane, from -78 deg C to RT, 2 h
3: 79 percent / aq. NaOH, aq. H2O2 / H2O / 1 h
4: 81 percent / sulfuryl chloride / diethyl ether
With
hydrogenchloride; sodium hydroxide; n-butyllithium; sulfuryl dichloride; dihydrogen peroxide; N,N-dimethyl-formamide;
In
diethyl ether; water;
DOI:10.1021/jo00229a011
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) Na, 2.) copper(I) iodide / 1.) 15 min, 2.) DMF, reflux, 4 h
2: 79 percent / aq. NaOH, aq. H2O2 / H2O / 1 h
3: 81 percent / sulfuryl chloride / diethyl ether
With
sodium hydroxide; copper(l) iodide; sulfuryl dichloride; dihydrogen peroxide; sodium;
In
diethyl ether; water;
DOI:10.1021/jo00229a011
