2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydron;chloride

Base Information

• Chemical Name: 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydron;chloride
• CAS No.: 14919-77-8
• Molecular Formula: C10H15N3O5^.HCl
• Molecular Weight: 293.74
• Hs Code.: 29280000
• Mol file: 14919-77-8.mol

Synonyms:2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydron;chloride;14046-64-1;SCHEMBL16516192;AKOS026750132

Chemical Property of 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydron;chloride

Chemical Property:

• Appearance/Colour: white crystalline solid
• Melting Point: 146 °C
• Boiling Point: 574.2 °C at 760 mmHg
• Flash Point: 301 °C
• PSA: 148.07000
• LogP: 0.52790
• Storage Temp.: -20°C Freezer
• Sensitive.: Light Sensitive
• Solubility.: H2O: 10 mg/mL
• Water Solubility.: Soluble in water, dimethyl sulfoxide and methanol. Insoluble in ethanol and acetone.
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 293.0778483
• Heavy Atom Count: 19
• Complexity: 278

Purity/Quality:

98% ^*data from raw suppliers

Benserazide, Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [H+].C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.[Cl-]
• Description: Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It is also unable to cross the blood-brain barrier. As a result, benserazide blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. Benserazide is often combined with L-DOPA in patients with Parkinson’s disease.
• Uses: Used as antiparkinsonian. A peripheral decarboxylase inhibitor Antiparkinsonian;DOPA decarboxylase inhibitor Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a peripheral decarboxylase inhibitor. It is used as an inhibitor for aromatic L-aminoacid decarboxylase. Further, it serves as an inhibitor of tyrosine hydroxylase (TH) and Tryptophan hydroxylase (TPH) inhibitor.