2-Sulfobenzoic anhydride

Base Information

• Chemical Name: 2-Sulfobenzoic anhydride
• CAS No.: 81-08-3
• Deprecated CAS: 27396-44-7,4377-89-3,4377-89-3
• Molecular Formula: C7H4O4S
• Molecular Weight: 184.172
• Hs Code.: 29163900
• European Community (EC) Number: 201-322-6
• NSC Number: 49162,11208
• UNII: 0SWH68IQ5W
• DSSTox Substance ID: DTXSID4038681
• Nikkaji Number: J192.582B,J40.203F
• Wikidata: Q27037740
• Mol file: 81-08-3.mol

Synonyms:2-sulfobenzoic acid cyclic anhydride;2-sulfobenzoic anhydride;2-sulfobenzoic cyclic anhydride;o-sulfobenzoic anhydride

Chemical Property of 2-Sulfobenzoic anhydride

Chemical Property:

• Appearance/Colour: white to beige crystals or crystalline powder
• Melting Point: 116-127 °C
• Refractive Index: 1.637
• Boiling Point: 314.7 °C at 760 mmHg
• Flash Point: 140.6 °C
• PSA: 68.82000
• Density: 1.635 g/cm³
• LogP: 1.62650
• Storage Temp.: Store below +30°C.
• Sensitive.: Moisture Sensitive
• Solubility.: soluble in Toluene
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 183.98302978
• Heavy Atom Count: 12
• Complexity: 300

Purity/Quality:

98% ^*data from raw suppliers

2-Sulfobenzoic Anhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-20/21/22
• Safety Statements: 22-24/25-45-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=O)OS2(=O)=O
• Uses: Polymerization inhibitor.

Technology Process of 2-Sulfobenzoic anhydride

There total 12 articles about 2-Sulfobenzoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

saccharin (81-07-2) → 2-sulfobenzoic acid cyclic anhydride (81-08-3)

Guidance literature:

With sulfuric acid; for 0.00888889h; Neat (no solvent); Microwave irradiation;

DOI:10.1080/00397911.2010.535946

Reference yield: 87.4%

Thiosalicylic acid (147-93-3) → 2-sulfobenzoic acid cyclic anhydride (81-08-3)

Guidance literature:

With sulfuryl dichloride; In acetonitrile; at 20 ℃; for 1.5h; Reagent/catalyst;

Reference yield: 65.0%

o-sulfobenzoic acid, monoammonium salt (6939-89-5) → 2-sulfobenzoic acid cyclic anhydride (81-08-3)

Guidance literature:

With thionyl chloride; In toluene; at 20 ℃; Reflux;

DOI:10.1080/17415990903480361

upstream raw materials:

2-sulfobenzoic acid

2-ethoxysulfonyl-benzoic acid ethyl ester

2-chlorosulfonylbenzoyl chloride

benzene

Downstream raw materials:

2-(methoxycarbonyl)benzenesulfonic acid

3,3-bis(4-hydroxy-2,5-dimethylphenyl)-3H-2,1λ⁶-benzoxathiole 1,1-dioxide

4-methyl-6,7-bis-(2-sulfo-benzoyloxy)-coumarin

2-dodecyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide

Refernces

• 1、 -. "Color change dye for ammonia gas detection and an ammonia gas detection sensor including the same". Paragraph 0169-0171. . Retrieved 2020/08/25.
• 2、 Tillu,Dumbre,Borate,Wakharkar,Choudhary. "Solvent-free one-pot synthesis of sulfonephthaleins from saccharin and phenols". experimental part. p. 1101 - 1107. Retrieved 2012/05/05.