2-Amino-5-hydroxypentanoic acid

Base Information

• Chemical Name: 2-Amino-5-hydroxypentanoic acid
• CAS No.: 533-88-0
• Molecular Formula: C5H11NO3
• Molecular Weight: 133.147
• Hs Code.: 2922509090
• NSC Number: 206265,20896
• UNII: PKG8I0M67E
• DSSTox Substance ID: DTXSID901315938
• Nikkaji Number: J6.335E
• Wikidata: Q27286597
• Metabolomics Workbench ID: 45021
• Mol file: 533-88-0.mol

Synonyms:2-amino-5-hydroxypentanoic acid;2-amino-5-hydroxyvaleric acid;2-amino-5-hydroxyvaleric acid, (DL)-isomer;2-amino-5-hydroxyvaleric acid, (L)-isomer;5-hydroxy-2-aminovalerate;5-hydroxy-2-aminovaleric acid;5-hydroxynorvaline;5-OH-2-NH2-valerate;alpha-amino-delta-hydroxyvaleric acid;HAVA-5 cpd

Chemical Property of 2-Amino-5-hydroxypentanoic acid

Chemical Property:

• Vapor Pressure: 7.36E-05mmHg at 25°C
• Melting Point: 218-220℃
• Refractive Index: 1.504
• Boiling Point: 306.1 °C at 760 mmHg
• PKA: 2.51±0.24(Predicted)
• Flash Point: 138.9 °C
• PSA: 83.55000
• Density: 1.241 g/cm³
• LogP: -0.12890
• XLogP3: -4.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 133.07389321
• Heavy Atom Count: 9
• Complexity: 94.2

Purity/Quality:

99% ^*data from raw suppliers

PENTAHOMOSERINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(CC(C(=O)O)N)CO

Technology Process of 2-Amino-5-hydroxypentanoic acid

There total 9 articles about 2-Amino-5-hydroxypentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glutamic acid 5-ethyl ester (45025-28-3) → 2-amino-5-hydroxyvaleric acid (533-88-0)

Guidance literature:

With tetrahydrofuran; lithium borohydride;

Reference yield:

→ 2-amino-5-hydroxyvaleric acid (533-88-0)

Guidance literature:

With hydrogenchloride;

Reference yield:

1,3-dibromo-propane (109-64-8) → 2-amino-5-hydroxyvaleric acid (533-88-0)

Guidance literature:

at 165 - 170 ℃; ueber mehreren Stufen;

upstream raw materials:

2,3-dihydro-2H-furan

4-butanolide

oxalic acid diethyl ester

glutamic acid 5-ethyl ester

Downstream raw materials:

5-hydroxy-2-(N'-phenyl-ureido)-valeric acid

2-benzoylamino-5-hydroxy-valeric acid

methyl 1-ethylpyrrolidine-2-carboxylate

1-ethyl-2-pyrrolidinemethanamine

Refernces