Galactose-6-phosphate

Base Information

• Chemical Name: Galactose-6-phosphate
• CAS No.: 6665-00-5
• Molecular Formula: C₆H₁₃O₉P
• Molecular Weight: 260.138
• DSSTox Substance ID: DTXSID401314709
• Nikkaji Number: J92.786D
• Metabolomics Workbench ID: 51020
• Mol file: 6665-00-5.mol

Synonyms:galactose-6-phosphate;galactose-6-phosphate, barium salt (1:1), (D)-isomer;galactose-6-phosphate, monosodium salt (1:1), (D)-isomer

Chemical Property of Galactose-6-phosphate

Chemical Property:

• Vapor Pressure: 1.1E-20mmHg at 25°C
• Refractive Index: 1.586
• Boiling Point: 667.8 °C at 760 mmHg
• PKA: 1.84±0.10(Predicted)
• Flash Point: 357.7 °C
• PSA: 166.72000
• Density: 1.832 g/cm³
• LogP: -3.10440
• Storage Temp.: 2-8°C
• XLogP3: -4.5
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 260.02971899
• Heavy Atom Count: 16
• Complexity: 263

Purity/Quality:

99%, ^*data from raw suppliers

D-Galactose 6-phosphate lithium salt ≥90% (TLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(C(C(C=O)O)O)O)O)OP(=O)(O)O
• Isomeric SMILES: C([C@H]([C@@H]([C@@H]([C@H](C=O)O)O)O)O)OP(=O)(O)O

Technology Process of Galactose-6-phosphate

There total 21 articles about Galactose-6-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

D-glucose (50-99-7) + phosphoenolpyruvic acid (138-08-9) → D-glucose 6-phosphate (56-73-5,3672-15-9,6665-00-5,82259-50-5,89396-13-4,92418-43-4,136376-93-7,136376-97-1,136377-00-9,136377-02-1,136377-04-3,136377-07-6,136377-08-7,136377-11-2,136377-13-4,136377-14-5,136457-25-5) + piruvate (57-60-3)

Guidance literature:

With ammonium sulfate; NAD; pyruvate kinase e; hexokinase; In hexane; water; for 32h; membran-enclosed enzymatic catalysis;

DOI:10.1021/ja00238a067

Reference yield:

D-fructose-6-phosphate (643-13-0,4300-29-2,6814-87-5,6934-25-4,52050-07-4,67424-99-1,73544-42-0,136598-62-4,136598-64-6,136598-65-7,136598-66-8) → D-glucose 6-phosphate (56-73-5,3672-15-9,6665-00-5,82259-50-5,89396-13-4,92418-43-4,136376-93-7,136376-97-1,136377-00-9,136377-02-1,136377-04-3,136377-07-6,136377-08-7,136377-11-2,136377-13-4,136377-14-5,136457-25-5)

Guidance literature:

phosphpoglucoisomerase; Rate constant; with 0.1 M sodium arsenate;

DOI:10.1021/jo00262a021

Reference yield:

D-glucose (50-99-7) → D-glucose 6-phosphate (56-73-5,3672-15-9,6665-00-5,82259-50-5,89396-13-4,92418-43-4,136376-93-7,136376-97-1,136377-00-9,136377-02-1,136377-04-3,136377-07-6,136377-08-7,136377-11-2,136377-13-4,136377-14-5,136457-25-5)

Guidance literature:

With phosphoric acid; water; toluene; Isolierung aus dem bei der Vergaerung mit Hefe in Loesung vom pH 7 erhaltenen Reaktionsgemisch;

upstream raw materials:

Sorbitol 6-phosphate

D-glucose

D-Fructose

5,6-anhydro-1,2-O-isopropylidene-α-D-glucofuranose

Downstream raw materials:

D-glucose

phosphoric acid

Sorbitol 6-phosphate

D-fructose-6-phosphate

Refernces

• 1、 Baykov, Alexander A.,Kolomijtseva, Galina Ya.,Kurilova, Svetlana A.,Nazarova, Tatiana I.,Petukhova, Anastasia F.,Rodina, Elena V.,Vorobjeva, Natalia N.. "A novel, cupin-type phosphoglucose isomerase in Escherichia coli". . . Retrieved 2020/04/01.
• 2、 Figueroa, Carlos M.,Iglesias, Alberto A.. "Aldose-6-phosphate reductase from apple leaves: Importance of the quaternary structure for enzyme activity". experimental part. p. 81 - 88. Retrieved 2010/12/25.