2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene

Base Information

• Chemical Name: 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene
• CAS No.: 59649-47-7
• Molecular Formula: C₂₁H₁₈O₂
• Molecular Weight: 302.373
• Mol file: 59649-47-7.mol

Synonyms:2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene

Chemical Property of 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene

There total 5 articles about 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-(1,3-Diphenyl-3-oxopropyl)cyclohexane-1,3-dione (53852-96-3) → 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene (59649-47-7)

Guidance literature:

With acetic anhydride; other reagent : glacial acetic acid;

Reference yield: 91.0%

1,3-cylohexanedione (504-02-9) + benzalacetophenone (94-41-7) → 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene (59649-47-7)

Guidance literature:

With tin(II) trifluoromethanesulfonate; tert-butylammonium hexafluorophosphate(V); In neat (no solvent); at 120 ℃; for 3h; Green chemistry;

DOI:10.1016/j.tetlet.2015.02.023

Reference yield: 86.0%

1,3-cylohexanedione (504-02-9) + benzaldehyde (100-52-7) + phenylacetylene (536-74-3) → 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene (59649-47-7)

Guidance literature:

With Fe₃O₄/SiO₂; In neat (no solvent); at 100 ℃; for 2h; Reagent/catalyst; Temperature; Catalytic behavior;

DOI:10.1039/d0ob00284d

upstream raw materials:

2-(1,3-Diphenyl-3-oxopropyl)cyclohexane-1,3-dione

1,3-cylohexanedione

benzalacetophenone

1,3-diphenyl-1-propyn-3-ol

Downstream raw materials:

2,4-diphenyl-5-oxo-1-bicyclo<4.4.0>dec-9-ene

2,4-Diphenyl-octahydro-chromene

2,4-diphenyl-4,6,7,8-tetrahydroquinolin-5(1H)-one

oxime of 2,4-diphenyl-5-oxo-5,6,7,8-tetrahydroquinoline

Refernces

• 1、 Yaragorla, Srinivasarao,Saini, Pyare Lal,Singh, Garima. "Alkaline earth metal catalyzed cascade, one-pot, solvent-free, and scalable synthesis of pyranocoumarins and benzo[b]pyrans". supporting information. p. 1649 - 1653. Retrieved 2015/03/14.
• 2、 Li, Qiang,Hu, Xueyuan,Li, Wei,Yang, Fei,Yang, Xiaoian,Sun, Lili,Zhou, Liping,Qi, Junsheng,Yu, Yu. "Preparation of 5-oxo-5,6,7,8-tetrahydro-4H-benzo-[b]-pyran derivatives in ionic liquids". experimental part. p. 331 - 333. Retrieved 2009/06/18.