1-Methoxy-2-propyl acetate

Base Information

• Chemical Name: 1-Methoxy-2-propyl acetate
• CAS No.: 108-65-6
• Deprecated CAS: 142300-82-1
• Molecular Formula: C6H12O3
• Molecular Weight: 132.159
• Hs Code.: H3OCH2CH(CH3)OC(O)CH3 MOL WT. 132.16
• European Community (EC) Number: 203-603-9
• ICSC Number: 0800
• NSC Number: 2207
• UN Number: 3271,1993
• UNII: PA7O2U6S2Q
• DSSTox Substance ID: DTXSID1026796
• Nikkaji Number: J38.089J
• Wikipedia: Propylene_glycol_methyl_ether_acetate
• Wikidata: Q2170375
• Metabolomics Workbench ID: 130595
• ChEMBL ID: CHEMBL3182130
• Mol file: 108-65-6.mol

Synonyms:methoxypropyl acetate;PGMEA cpd;propylene glycol methyl ether acetate

Chemical Property of 1-Methoxy-2-propyl acetate

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 3.7 mm Hg ( 20 °C)
• Melting Point: -87 °C
• Refractive Index: 1.401 - 1.403
• Boiling Point: 154.8 °C at 760 mmHg
• Flash Point: 47.9 °C
• PSA: 35.53000
• Density: 0.959 g/cm³
• LogP: 0.58440
• Storage Temp.: Flammables area
• Solubility.: water: soluble198g/L at 20°C
• Water Solubility.: 19.8 g/L (25 ºC)
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 132.078644241
• Heavy Atom Count: 9
• Complexity: 90.3
• Transport DOT Label: Flammable Liquid

Purity/Quality:

99% ^*data from raw suppliers

Propylene Glycol 1-Monomethyl Ether 2-Acetate >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,Xi
• Hazard Codes: T,Xi
• Statements: 61-10-36
• Safety Statements: 53-25-45

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Glycol Ethers (P Series)
• Canonical SMILES: CC(COC)OC(=O)C
• Inhalation Risk: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes and respiratory tract. Exposure at high levels could cause depression of the central nervous system.
• Effects of Long Term Exposure: The substance defats the skin, which may cause dryness or cracking.
• Description: Propylene glycol methyl ether acetate (PGMEA), also known as propylene glycol monomethyl ether acetate, with molecular formula of C6H12O3, is a colorless hygroscopic liquid with special smell. It is a non pollution solvent with multi-functional groups. It is mainly used as the solvent of ink, paint, ink, textile dye and textile oil agent, and also as the cleaning agent in the production of LCD. Flammable, may form explosive vapor / air mixture above 42 ° C. Propylene glycol methyl ether acetate (PGMEA) is an advanced solvent. Its molecule has both ether bond and carbonyl. Carbonyl forms the structure of ester and contains alkyl at the same time. In the same molecule, there are both non-polar and polar parts. The functional groups of these two parts not only restrict and repel each other, but also play their inherent roles. Therefore, it has a certain solubility for non-polar substances and polar substances.1-Methoxy-2-propyl acetate (PGMEA) is a material contains polar groups and non polar group , has good ability of dissolving and coupling, commonly used in solvent based coatings and screen printing ink. Using dipropylene glycol methyl ether and acetic acid as raw material, under the catalysis of solid acid, via esterification reaction to generated crude product and its high purity PGMEA after distillation.
• Uses: 1,2-Propanediol monomethyl ether acetate is used as a solvent for paints, inks, lacquers, varnishes, cleaners and coatings. It is also used as a solvent for degreasing circuit boards and in food contact applications. Further, it is used in photoresist formulations in the semiconductor industry.

Technology Process of 1-Methoxy-2-propyl acetate

There total 9 articles about 1-Methoxy-2-propyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

→ propylene glycol methyl ether acetate (108-65-6,142300-82-1)

Guidance literature:

In methanol; hexane; water; butanone;

Reference yield: 60.0%

2-(1-methoxycarbonyl-1-methylethylazo)-2-methylpropionic acid methyl ester (2589-57-3) → propylene glycol methyl ether acetate (108-65-6,142300-82-1)

Guidance literature:

In methanol; hexane; butanone;

Reference yield:

1-methoxy-2-propanol (107-98-2) + acetic acid (64-19-7,77671-22-8) → propylene glycol methyl ether acetate (108-65-6,142300-82-1)

Guidance literature:

at 98 ℃; under 130.002 Torr; Concentration;

upstream raw materials:

1-methoxy-2-propanol

acetic anhydride

sodium methylate

methyloxirane

Downstream raw materials:

(E)-1-Methoxy-1-propen

methylallylether

methyl (Z)-prop-1-enyl ether

(S)-1-Methoxy-propan-2-ol

Refernces

• 1、 -. "Photoresist composition, resist pattern-forming method, compound, acid generating agent, and photodegradable base". . . Retrieved 2016/05/24.
• 2、 -. "Pattern forming method, chemical amplification resist composition and resist film". . . Retrieved 2015/02/25.