(R)-9-(2-Hydroxypropyl)adenine

Base Information Edit

Chemical Name:(R)-9-(2-Hydroxypropyl)adenine
CAS No.:14047-28-0
Molecular Formula:C8H11N5O
Molecular Weight:193.208
Hs Code.:2933990090
UNII:43H6SBP55W
DSSTox Substance ID:DTXSID20332178
Nikkaji Number:J3.287.859H
Wikidata:Q27096355
Metabolomics Workbench ID:147325
Mol file:14047-28-0.mol

Synonyms:14047-28-0;(R)-9-(2-Hydroxypropyl)adenine;(R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol;(R)-(+)-9-(2-HYDROXYPROPYL)ADENINE;(2R)-1-(6-aminopurin-9-yl)propan-2-ol;(R)-(-)-9-(2-Hydroxypropyl)adenine;9-HYDROXYPROPYLADENINE, R-ISOMER;9-(2-Hydroxypropyl)adenine, (R)-;UNII-43H6SBP55W;43H6SBP55W;9H-Purine-9-ethanol, 6-amino-alpha-methyl-, (alphaR)-;(R)-9-[2-(Hydroxypropyl] Adenine;MFCD07369451;R-9-(2-hydroxypropyl)adenine [WHO-DD];9H-Purine-9-ethanol, 6-amino-alpha-methyl-, D-;9H-Purine-9-ethanol, 6-amino-alpha-methyl-, (R)-;(R)-9-(2-Hydroxypropyl)adenine (Desphosphoryltenofovir);(R)-9-[2-(Hydroxypropyl] Adenine(Desphosphoryl Tenofovir);D-(-)-9-(2-HYDROXYPROPYL)ADENINE;(Desphosphoryl Tenofovir);D0X1HX;R-9-(2-hydroxypropyl)adenine;SCHEMBL1393316;R-9-(2-Hydroxy Propyl)adenine;DTXSID20332178;(R)-9[2-(hydroxy)propyl]adenine;AMY40726;(R)-9-[2-(hydroxy)propyl]adenine;(r)-9-[2-(hydroxyl)propyl]adenine;AKOS006286534;AKOS015855516;AC-8499;CS-O-32069;DB02765;(R)-6-Amino-9-(2-hydroxypropyl)purine;DS-16283;CS-0040479;H1291;(R)-9-(2-hydroxypropyl)adenine, AldrichCPR;(2R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol;(R)-1-(6-Amino-9H-purine-9-yl)-2-propanol;(alphaR)-6-Amino-alpha-methyl-9H-purine-9-ethanol;W-201193;Q27096355;9H-Purine-9-ethanol, 2-amino-.alpha.-methyl-, (a9R)-;9H-PURINE-9-ETHANOL, 6-AMINO-.ALPHA.-METHYL-, D-;9H-PURINE-9-ETHANOL, 6-AMINO-.ALPHA.-METHYL-, (R)-;9H-PURINE-9-ETHANOL, 6-AMINO-.ALPHA.-METHYL-, (.ALPHA.R)-

Suppliers and Price of (R)-9-(2-Hydroxypropyl)adenine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-9-[2-(Hydroxypropyl]Adenine(DesphosphorylTenofovir)
1g
$ 185.00

TCI Chemical
(R)-9-(2-Hydroxypropyl)adenine >98.0%(HPLC)(T)
1g
$ 27.00

TCI Chemical
(R)-9-(2-Hydroxypropyl)adenine >98.0%(HPLC)(T)
5g
$ 38.00

Medical Isotopes, Inc.
(R)-9-[2-(Hydroxypropyl]Adenine
50 mg
$ 1800.00

Matrix Scientific
(R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol 95%
250mg
$ 1074.00

Matrix Scientific
(R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol 95%
1g
$ 2146.00

CSNpharm
(R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol
100mg
$ 45.00

Crysdot
(R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol 97%
100g
$ 113.00

Chemcia Scientific
(R)-1-(6-Amino-purin-9-yl)-propan-2-ol 95%
100 G
$ 250.00

Chemcia Scientific
(R)-1-(6-Amino-purin-9-yl)-propan-2-ol 95%
500 G
$ 825.00

Total 189 raw suppliers

Chemical Property of (R)-9-(2-Hydroxypropyl)adenine Edit

Chemical Property:

Vapor Pressure:3.6E-09mmHg at 25°C
Melting Point:193 °C
Refractive Index:1.752
Boiling Point:457.7 °C at 760 mmHg
PKA:14.42±0.20(Predicted)
Flash Point:230.6 °C
PSA：89.85000
Density:1.57 g/cm³
LogP:0.37050
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated)
XLogP3:-0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:193.09635999
Heavy Atom Count:14
Complexity:202

Purity/Quality:

99% ^*data from raw suppliers

(R)-9-[2-(Hydroxypropyl]Adenine(DesphosphorylTenofovir) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CN1C=NC2=C(N=CN=C21)N)O
Isomeric SMILES:C[C@H](CN1C=NC2=C(N=CN=C21)N)O
Uses (R)-9-[2-(Hydroxypropyl] Adenine (Desphosphoryl Tenofovir) (cas# 14047-28-0) is a useful reagent for preparing the antiviral drug tenofovir.

Technology Process of (R)-9-(2-Hydroxypropyl)adenine

There total 24 articles about (R)-9-(2-Hydroxypropyl)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.7%

: (R)-6-acetyl-9-(2-hydroxypropyl)adenine

: 14047-28-0,712-00-5
(R)-9-(2-hydroxypropyl)adenine

Guidance literature:: With sodium hydroxide; In water; at 93 ℃; for 2h; Temperature;

Reference yield: 96.3%

: 180587-74-0
(R)-1-(6-chloro-9H-purin-9-yl) propan-2-ol

: 14047-28-0,712-00-5
(R)-9-(2-hydroxypropyl)adenine

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane; at 100 - 110 ℃; Sealed tube; Large scale;

Reference yield: 95.4%

: 1464851-21-5
(Z)-6-amino-9-(prop-1-en-1-yl)-9H-purine

: 14047-28-0,712-00-5
(R)-9-(2-hydroxypropyl)adenine

Guidance literature:: With D-tartaric acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; Concentration; Reagent/catalyst; Temperature;