5-Bromopentan-1-ol

Base Information

• Chemical Name: 5-Bromopentan-1-ol
• CAS No.: 34626-51-2
• Molecular Formula: C5H11BrO
• Molecular Weight: 167.046
• Hs Code.: 29055900
• European Community (EC) Number: 628-068-2
• DSSTox Substance ID: DTXSID3067861
• Nikkaji Number: J25.069D
• Wikidata: Q72448959
• Mol file: 34626-51-2.mol

Synonyms:5-bromopentan-1-ol;34626-51-2;5-bromo-1-pentanol;1-Pentanol, 5-bromo-;5-bromopentanol;C5H11BrO;1-bromo-5-hydroxypentane;5-bromo-pentanol;5-bromo-l-pentanol;SCHEMBL179881;C5-H11-Br-O;DTXSID3067861;MFCD00061101;AKOS009158914;CS-W007393;AS-30544;BP-31244;AM20090543;B1848;FT-0648064;EN300-57110;5-Bromo-1-pentanol, technical, >=80% (GC);A24616;J-650189

Chemical Property of 5-Bromopentan-1-ol

Chemical Property:

• Vapor Pressure: 0.067mmHg at 25°C
• Refractive Index: n20/D 1.482
• Boiling Point: 203.5 °C at 760 mmHg
• PKA: 15.11±0.10(Predicted)
• Flash Point: 93.3 °C
• PSA: 20.23000
• Density: 1.371 g/cm³
• LogP: 1.54390
• Storage Temp.: Freezer
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 165.99933
• Heavy Atom Count: 7
• Complexity: 31.3

Purity/Quality:

99% ^*data from raw suppliers

5-Bromopentanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 36/37/38-22-10
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCO)CCBr

Technology Process of 5-Bromopentan-1-ol

There total 14 articles about 5-Bromopentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-bromopentanoic acid (2067-33-6) → 5-bromopentan-1-ol (34626-51-2)

Guidance literature:

With dimethylsulfide borane complex; In tetrahydrofuran; at 45 ℃; for 1h; Cooling with ice;

DOI:10.3390/molecules26144204

Reference yield: 95.0%

TETRAHYDROPYRANE (142-68-7) → 5-bromopentan-1-ol (34626-51-2)

Guidance literature:

With Acetyl bromide; zinc; Heating;

DOI:10.1016/0040-4039(96)01516-X

Reference yield: 90.0%

5-bromovaleric acid methyl ester (5454-83-1) → 5-bromopentan-1-ol (34626-51-2)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; Petroleum ether; 1.) 10-20 deg C, 2.) room temperature, 10 min;

DOI:10.1080/00397919608003721

upstream raw materials:

ethyl 5-bromovalerate

5-bromo-1-pentanyl acetate

TETRAHYDROPYRANE

1 ,5-pentanediol

Downstream raw materials:

5-[4-(4-Methoxy-phenylazo)-phenoxy]-pentan-1-ol

5-hydroxypentyl phenyl selenide

1-hydroxy-6-heptyne

5-Hydroxy-pentyl-diphenylphosphin

Refernces

• 1、 Keinan,Sahai,Shvily. "Diiodosilane. 4. Direct reduction of ketals and acetals in the presence of unprotected carbonyls. A case of inverted chemoselectivity". . p. 641 - 643. Retrieved 1991.
• 2、 Huefner, Antje,Presser, Armin. "Stereoselective synthesis of isomers of the naturally occurring 13-hydroxy-2,4,9-tetradecatrienic acid I". . p. 931 - 936. Retrieved 1998.
• 3、 Maity, D. K.,Mohan, H.,Chattopadhyay, S.,Mittal, J. P.. "Formation, Stability, and Reactivity of Radical Cations of 1-Bromo-n-chloroalkanes in Aqueous Solution: A Pulse Radiolysis Study". . p. 12195 - 12203. Retrieved 1995.
• 4、 Ho, Angel,Pounder, Austin,Koh, Samuel,Macleod, Matthew P.,Carlson, Emily,Tam, William. "Acid-Catalyzed Intramolecular Ring-Opening Reactions of Cyclopropanated Oxabenzonorbornadienes with Carboxylic Acid Nucleophiles". . p. 1422 - 1430. Retrieved 2021/12/02.
• 5、 Afroudakis, Pantelis,Barrias, Emile,Bifeld, Eugenia,Borsari, Chiara,Calogeropoulou, Theodora,Clos, Joachim,Costi, Maria Paola,Ellinger, Bernhard,Fotopoulou, Theano,Fragiadaki, Irini,Georgikopoulou, Kalliopi,Gul, Sheraz,Hachenberg, Julia,Kuzikov, Maria,Magoulas, George E.,Prousis, Kyriakos C.,Roussaki, Marina,Santarem, Nuno,Scoulica, Effie,Tejera Nevado, Paloma,da Silva, Anabela Cordeiro,de Souza, Wanderley. "Design, synthesis and antiparasitic evaluation of click phospholipids". . . Retrieved 2021/07/26.