benzoate-N-butyl-N-methylamide

Base Information

• Chemical Name: benzoate-N-butyl-N-methylamide
• CAS No.: 79242-10-7
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.273
• Mol file: 79242-10-7.mol

Synonyms:benzoate-N-butyl-N-methylamide

Chemical Property of benzoate-N-butyl-N-methylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoate-N-butyl-N-methylamide

There total 13 articles about benzoate-N-butyl-N-methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-n-butyl-N-methylamine (110-68-9) + phenyl(2-thioxothiazolidin-3-yl)methanone (70326-37-3) → benzoate-N-butyl-N-methylamide (79242-10-7)

Guidance literature:

In dichloromethane; for 0.1h; Ambient temperature;

Reference yield: 77.0%

N-n-butyl-N-methylamine (110-68-9) + benzyl alcohol (100-51-6,185532-71-2) → benzoate-N-butyl-N-methylamide (79242-10-7)

Guidance literature:

With tert.-butylhydroperoxide; C₅H₈AgClN₂O₄S₂; In ethanol; water; at 60 ℃; for 18h;

DOI:10.1016/j.tetlet.2019.02.024

Reference yield: 72.0%

n-butyllithium (109-72-8,29786-93-4) + benzoyl chloride (98-88-4) + N,0-dimethylhydroxylamine (1117-97-1) → benzoate-N-butyl-N-methylamide (79242-10-7)

Guidance literature:

With pyridine; water; methyllithium; In diethyl ether; hexane;

DOI:10.1021/ja00279a058

upstream raw materials:

1-bromo-butane

N-methylbenzamide

n-butyllithium

benzoyl chloride

Downstream raw materials:

N-tert-butylperoxymethyl-N-methylbenzamide

N-chloromethyl-N-methylbenzamide

N-Formyl-N-methylbenzamide

N-methylbenzamide

Refernces

• 1、 Tóth, Balázs L.,Sályi, Gerg?,Domján, Attila,Egyed, Orsolya,Bényei, Attila,Gonda, Zsombor,Novák, Zoltán. "Z-Selective Fluoroalkenylation of (Hetero)Aromatic Systems by Iodonium Reagents in Palladium-Catalyzed Directed C?H Activation". . p. 348 - 354. Retrieved 2021/11/09.
• 2、 Soule, Jean-Francois,Miyamura, Hiroyuki,Kobayashi, Shu. "Direct amidation from alcohols and amines through a tandem oxidation process catalyzed by heterogeneous-polymer-incarcerated gold nanoparticles under aerobic conditions". supporting information. p. 2614 - 2626. Retrieved 2013/11/19.