Chlorodiisopropylphosphine

Base Information

• Chemical Name: Chlorodiisopropylphosphine
• CAS No.: 40244-90-4
• Molecular Formula: C6H14ClP
• Molecular Weight: 152.604
• Hs Code.: 29310099
• European Community (EC) Number: 629-426-0
• UNII: 5FG5N54CYB
• DSSTox Substance ID: DTXSID10337132
• Nikkaji Number: J121.063G
• Wikipedia: Chlorodiisopropylphosphine
• Wikidata: Q18387387
• Mol file: 40244-90-4.mol

Synonyms:chlorodiisopropylphosphine

Chemical Property of Chlorodiisopropylphosphine

Chemical Property:

• Appearance/Colour: Colorless to light yellow liquid
• Vapor Pressure: 3.16mmHg at 25°C
• Refractive Index: n20/D 1.475(lit.)
• Boiling Point: 160 °C at 760 mmHg
• Flash Point: 3.9 °C
• PSA: 13.59000
• Density: 0.959 g/mL at 25 °C(lit.)
• LogP: 3.43890
• Storage Temp.: Refrigerator
• Sensitive.: air sensitive, moisture sensitiv
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 152.0521651
• Heavy Atom Count: 8
• Complexity: 53.5

Purity/Quality:

99% ^*data from raw suppliers

Chlorodiisopropylphosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, C
• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 16-26-27-36/37/39-45-1

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)P(C(C)C)Cl
• Uses: Chlorodiisopropylphosphine can be used: To synthesize p-styryldiisopropylphosphine by reacting with 4-chlorostyrene via Grignard reaction.As a phosphination reagent in combination with [Cp2Zr(1-butene)(DMAP)] (Cp=cyclopentadienyl; DMAP= 4-(dimethylamino)pyridine)) for the zirconophosphination of alkynes to form zirconoalkenylphosphines.A luminescent mixed-donor platinum POCN pincer complex via cyclometalation process.

Technology Process of Chlorodiisopropylphosphine

There total 9 articles about Chlorodiisopropylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

Dichloromethyl methyl ether (4885-02-3) + (diethoxymethyl)diisopropylphosphine oxide (95987-39-6) → chloroethane (75-00-3) + Methyl formate (107-31-3) + Chlorodiisopropylphosphane (40244-90-4) + formic acid ethyl ester (109-94-4)

Guidance literature:

at 60 ℃; for 1h; Product distribution; argon atmosphere;

Reference yield:

isopropylmagnesium chloride (1068-55-9) → Chlorodiisopropylphosphane (40244-90-4)

Guidance literature:

With phosphorus trichloride; In diethyl ether;

Reference yield:

diisopropylphosphinous iodide (59612-04-3) → Chlorodiisopropylphosphane (40244-90-4)

Guidance literature:

With diethyl phosphorylchloridite; In diethyl ether;

upstream raw materials:

isopropyl chloride

dichloroisopropylphosphine

diisopropylphosphinous iodide

isopropylmagnesium chloride

Downstream raw materials:

diisopropylphosphinous acid trimethylhydrazide

C₁₂H₁₉ClNP

Cy₂PCH₂PPrⁱ2

4,6-di-tert-butyl-2-(diisopropylphosphanyl)phenol

Refernces

• 1、 Mueller, Lutz-Peter,Zanin, Andreas,Mont, Wolf-Walther du,Jeske, Joerg,Martens, Reiner,Jones, Peter G.. "Reactions of Silicon-Silicon Bonds, VI. Reductive Trichlorosilylation Reactions Leading to Alkyl- and Dialkylaminobis(trichlorosilyl)phosphanes". . p. 377 - 384. Retrieved 2007/10/03.
• 2、 Veits, Yu. A.,Neganova, E. G.,Borisenko, A. A.,Foss, V. L.. "SYNTHESIS AND PROPERTIES OF ACYLTRIALKYLDIPHOSPHINES". . p. 1810 - 1816. Retrieved 2007/10/02.