(+)-N-Benzoylglutamic acid

Base Information

• Chemical Name: (+)-N-Benzoylglutamic acid
• CAS No.: 58094-18-1
• Molecular Formula: C12H13NO5
• Molecular Weight: 251.239
• Hs Code.: 2924299090
• European Community (EC) Number: 624-214-4
• Nikkaji Number: J365.204A
• Wikidata: Q76416797
• Mol file: 58094-18-1.mol

Synonyms:(+)-N-Benzoylglutamic acid;58094-18-1;benzoyl-d-glutamic acid;(2R)-2-benzamidopentanedioic acid;(2R)-2-(phenylformamido)pentanedioic acid;SCHEMBL715646;(R)-2-benzamidopentanedioic acid;(R)-(+)-N-benzoylglutamic acid;LPJXPACOXRZCCP-SECBINFHSA-N;(R)-2-(Benzoylamino)glutaric acid;CS-0343865;(+)-N-Benzoylglutamic acid, synthetic, 97%;EN300-59227

Chemical Property of (+)-N-Benzoylglutamic acid

Chemical Property:

• Vapor Pressure: 1.81E-13mmHg at 25°C
• Melting Point: 130-135 °C(lit.)
• Refractive Index: 1.577
• Boiling Point: 562 °C at 760 mmHg
• PKA: 3.61±0.10(Predicted)
• Flash Point: 293.7 °C
• PSA: 103.70000
• Density: 1.354 g/cm³
• LogP: 1.12530
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 251.07937252
• Heavy Atom Count: 18
• Complexity: 322

Purity/Quality:

98%,99%, ^*data from raw suppliers

(+)-N-Benzoylglutamic acid synthetic, 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC(CCC(=O)O)C(=O)O
• Isomeric SMILES: C1=CC=C(C=C1)C(=O)N[C@H](CCC(=O)O)C(=O)O

Technology Process of (+)-N-Benzoylglutamic acid

There total 12 articles about (+)-N-Benzoylglutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzoylglutamic acid (6094-36-6,58094-18-1,88613-20-1,6460-81-7) → L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + N-benzoyl-L-glutamic acid (6094-36-6) + N-benzoyl-D-glutamic acid (58094-18-1)

Guidance literature:

With D-glucose; corn steep liquor; fungus Beauveria bassiana ATCC 7159; In ethanol; water; for 72h; Title compound not separated from byproducts; Enzymatic reaction;

DOI:10.1007/s007060070095

Reference yield:

Glutamic acid (617-65-2,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + benzoyl chloride (98-88-4) → N-benzoylglutamic acid (6094-36-6,58094-18-1,88613-20-1,6460-81-7)

Guidance literature:

With water; sodium hydrogencarbonate; benzoyl-dl-glutamic acid;

Reference yield:

→ N-benzoylglutamic acid (6094-36-6,58094-18-1,88613-20-1,6460-81-7)

Guidance literature:

With strychnidin-10-one; benzoyl-l-glutamic acid;

upstream raw materials:

N-thiobenzoyl-L-glutamic acid

Glutamic acid

benzoyl chloride

N-(cyclopent-2-en-1-yl)-benzamide

Downstream raw materials:

L-glutamic acid

N-benzoyl-L-glutamic acid

Glutamic acid

4-benzoylamino-5-oxo-hexanoic acid

Refernces

• 1、 Holland, Herbert L.,Andreana, Peter R.,Salehzadeh-Asl, Reza,Van Vliet, Aaron,Ihasz, Nancy J.,Brown, Frances M.. "Beauveria bassiana ATCC 7159 contains an L-specific α-amino acid benzamidase". . p. 667 - 672. Retrieved 2007/10/03.
• 2、 -. "Composition containing a penem or carbapenem antibiotic". . . Retrieved 2008/06/13.