4,4'-Dimethoxy-4''-nitrotriphenylamine

Base Information

• Chemical Name: 4,4'-Dimethoxy-4''-nitrotriphenylamine
• CAS No.: 20440-91-9
• Molecular Formula: C20H18N2O4
• Molecular Weight: 350.374
• Hs Code.: 2922299090
• Mol file: 20440-91-9.mol

Synonyms:Triphenylamine,4,4'-dimethoxy-4''-nitro- (8CI);4-Nitro-N,N-di(4-methoxyphenyl)benzenamine;4,4'-Dimethoxy-4''-nitrotriphenylamine;

Chemical Property of 4,4'-Dimethoxy-4''-nitrotriphenylamine

Chemical Property:

• Refractive Index: 1.631
• Boiling Point: 518.6 °C at 760 mmHg
• PKA: -4.91±0.50(Predicted)
• Flash Point: 267.4 °C
• PSA: 67.52000
• Density: 1.249 g/cm³
• LogP: 5.60500
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-Methoxy-N-(4-methoxyphenyl)-N-(4-nitrophenyl)aniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-Dimethoxy-4''-nitrotriphenylamine

There total 6 articles about 4,4'-Dimethoxy-4''-nitrotriphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

para-iodoanisole (696-62-8) + 4-nitro-aniline (100-01-6,104810-17-5) → 4-methoxy-N-(4-nitrophenyl)aniline (730-11-0) + 4,4’-dimethoxy-4’’-nitrotriphenylamine (20440-91-9)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 24h; Sealed tube;

DOI:10.1021/acs.joc.8b00620

Reference yield: 76.0%

1-bromo-4-methoxy-benzene (104-92-7) + 3-nitro-aniline (99-09-2) → 4,4’-dimethoxy-4’’-nitrotriphenylamine (20440-91-9)

Guidance literature:

With copper(l) iodide; potassium carbonate; pipecolic Acid; In N,N-dimethyl-formamide; at 110 ℃; for 24h;

DOI:10.1002/adsc.200606198

Reference yield: 75.0%

para-iodoanisole (696-62-8) + 4-nitro-aniline (100-01-6,104810-17-5) → 4,4’-dimethoxy-4’’-nitrotriphenylamine (20440-91-9)

Guidance literature:

With 18-crown-6 ether; copper; potassium carbonate; In 1,2-dichloro-benzene;

DOI:10.1039/b810750e

upstream raw materials:

para-iodoanisole

2-[(4-methoxyphenyl)amino]-5-nitrobenzoic acid

1-bromo-4-methoxy-benzene

3-nitro-aniline

Downstream raw materials:

C₂₇H₂₂N₄O₇

4-(3,5-diaminobenzamido)-4',4''-dimethoxytriphenylamine

Refernces

• 1、 Garnier, Tony,Danel, Mathieu,Magné, Valentin,Pujol, Anthony,Bénéteau, Valérie,Pale, Patrick,Chassaing, Stefan. "Copper(I)-USY as a Ligand-Free and Recyclable Catalyst for Ullmann-Type O-, N-, S-, and C-Arylation Reactions: Scope and Application to Total Synthesis". . p. 6408 - 6422. Retrieved 2018/05/31.
• 2、 Keller, Sascha G.,Pannwitz, Andrea,Schwizer, Fabian,Klehr, Juliane,Wenger, Oliver S.,Ward, Thomas R.. "Light-driven electron injection from a biotinylated triarylamine donor to [Ru(diimine)3]2+-labeled streptavidin". supporting information. p. 7197 - 7201. Retrieved 2016/08/05.