Chloromethyl butyl ether

Base Information

• Chemical Name: Chloromethyl butyl ether
• CAS No.: 2351-69-1
• Molecular Formula: C5H11ClO
• Molecular Weight: 122.595
• Hs Code.: 2909199090
• European Community (EC) Number: 852-154-0
• DSSTox Substance ID: DTXSID00455278
• Wikidata: Q72453105
• Mol file: 2351-69-1.mol

Synonyms:1-(chloromethoxy)butane;CHLOROMETHYL BUTYL ETHER;2351-69-1;Butane, 1-(chloromethoxy)-;Butane,1-(chloromethoxy)-;Chlormethylbutylather;butoxymethyl chloride;1-chloromethoxy-butane;chloromethyl-n-butyl ether;CHLOROMETHYLBUTYLETHER;SCHEMBL1127415;DTXSID00455278;NEFNOUUWYACOKP-UHFFFAOYSA-N;MFCD00040115;AKOS006272332;AS-80723;SY264650;FT-0690719;E78788;EN300-4274884

Chemical Property of Chloromethyl butyl ether

Chemical Property:

• Refractive Index: 1.4141-1.4208
• Boiling Point: 121oC
• Flash Point: 39oC
• PSA: 9.23000
• Density: 0.951
• LogP: 1.99940
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 122.0498427
• Heavy Atom Count: 7
• Complexity: 31.3

Purity/Quality:

99% ^*data from raw suppliers

CHLOROMETHYL BUTYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCOCCl

Technology Process of Chloromethyl butyl ether

There total 2 articles about Chloromethyl butyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-n-butyloxymethane (2568-90-3) + chloroform (67-66-3,8013-54-5) + di-tert-butyl peroxide (110-05-4) → dichloromethane (75-09-2) + n-Butyl chloride (109-69-3) + n-butyl formate (592-84-7) + butyraldehyde (123-72-8) + 1-(chloromethoxy)butane (2351-69-1) + tert-butyl alcohol (75-65-0)

Guidance literature:

at 130 ℃; for 1.5h; Product distribution; other concentration of reagents;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + butan-1-ol (71-36-3) → di-n-butyloxymethane (2568-90-3) + 1-(chloromethoxy)butane (2351-69-1)

Guidance literature:

With hydrogenchloride; Title compound not separated from byproducts;

Reference yield: 82.0%

N,N-Dimethyltrimethylsilylamine (2083-91-2) + 1-(chloromethoxy)butane (2351-69-1) → butoxytrimethylsilane (1825-65-6) + N,N-dimethyl(methylene)ammonium chloride (30354-18-8)

Guidance literature:

In diethyl ether; for 1h;

upstream raw materials:

di-n-butyloxymethane

chloroform

di-tert-butyl peroxide

formaldehyd

Downstream raw materials:

allyl n-butyl ether

(+/-)-butyl-(trans-2-chloro-cyclohexylmethyl)-ether

di-n-butyloxymethane

formaldehyd

Refernces

• 1、 Rol'nik, L. Z.,Kalashnikov, S. M.,Pastushenko, E. V.,Zlot-skii, S. S.,Imashev, U. B.,Rakhmankulov, D. L.. "FREE-RADICAL RECTIONS OF DIALKOXYMETHANES IN A CHLOROFORM MEDIUM". . p. 639 - 642. Retrieved 2007/10/02.