O-METHYL-UNDECAETHYLENE GLYCOL

Base Information

• Chemical Name: O-METHYL-UNDECAETHYLENE GLYCOL
• CAS No.: 114740-40-8
• Molecular Formula: C23H48O12
• Molecular Weight: 516.627
• Mol file: 114740-40-8.mol

Synonyms:2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-ol(6CI,9CI);2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol;O-Methyl-undecaethylene glycol;

Chemical Property of O-METHYL-UNDECAETHYLENE GLYCOL

Chemical Property:

• Vapor Pressure: 9.92E-15mmHg at 25°C
• Refractive Index: 1.456
• Boiling Point: 557.1 °C at 760 mmHg
• Flash Point: 290.7 °C
• PSA: 121.76000
• Density: 1.086 g/cm³
• LogP: -0.20890

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-Methoxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of O-METHYL-UNDECAETHYLENE GLYCOL

There total 6 articles about O-METHYL-UNDECAETHYLENE GLYCOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3,6,9,12,15,18,21-heptaoxadocosan-1-ol (4437-01-8) + 1,3,6,9,12-pentaoxa-2-thiacyclotetradecane 2,2-dioxide → methoxypolyethylene glycols-S-triphenylmethyl-L-cysteine dopamine (114740-40-8)

Guidance literature:

3,6,9,12,15,18,21-heptaoxadocosan-1-ol; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

1,3,6,9,12-pentaoxa-2-thiacyclotetradecane 2,2-dioxide; In tetrahydrofuran; mineral oil; at 20 ℃; for 12h; Inert atmosphere;

With sulfuric acid; In tetrahydrofuran; water; for 3h; Reflux;

DOI:10.1016/j.bmcl.2018.12.059

Reference yield:

Tetraethylene glycol (112-60-7) → methoxypolyethylene glycols-S-triphenylmethyl-L-cysteine dopamine (114740-40-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine; dmap; thionyl chloride / dichloromethane / 0 °C

2.1: sodium periodate; ruthenium(III) chloride trihydrate / dichloromethane; acetonitrile; water / 0 °C

3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 - 20 °C / Inert atmosphere

3.2: 12 h / 20 °C / Inert atmosphere

3.3: 3 h / Reflux

With dmap; sodium periodate; thionyl chloride; ruthenium(III) chloride trihydrate; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; water; acetonitrile; mineral oil;

DOI:10.1016/j.bmcl.2018.12.059

Reference yield:

1,3,6,9,12-pentaoxa-2-thiacyclotetradecane 2-oxide → methoxypolyethylene glycols-S-triphenylmethyl-L-cysteine dopamine (114740-40-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium periodate; ruthenium(III) chloride trihydrate / dichloromethane; acetonitrile; water / 0 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 - 20 °C / Inert atmosphere

2.2: 12 h / 20 °C / Inert atmosphere

2.3: 3 h / Reflux

With sodium periodate; ruthenium(III) chloride trihydrate; sodium hydride; In tetrahydrofuran; dichloromethane; water; acetonitrile; mineral oil;

DOI:10.1016/j.bmcl.2018.12.059

upstream raw materials:

octaethylene glycol monomethyl ether

3,6,9,12,15,18,21-heptaoxadocosan-1-ol

Tetraethylene glycol

Downstream raw materials:

3,6,9,12,15,18,21,24,27,30,33-undecaoxatetratriacontanoic acid

Refernces