2-Indanyl p-toluenesulfonate

Base Information

• Chemical Name: 2-Indanyl p-toluenesulfonate
• CAS No.: 17783-69-6
• Molecular Formula: C16H16 O3 S
• Molecular Weight: 288.367
• Hs Code.: 2906299090
• DSSTox Substance ID: DTXSID20427371
• Nikkaji Number: J2.107.240K
• Wikidata: Q82240028
• Mol file: 17783-69-6.mol

Synonyms:2-Indanyl p-toluenesulfonate;17783-69-6;2,3-dihydro-1H-inden-2-yl 4-methylbenzenesulfonate;1H-Inden-2-ol, 2,3-dihydro-, 2-(4-methylbenzenesulfonate);2-Indanyl p-toluenesulphonate;indan-2-yl tosylate;2-indanyl para-toluenesulfonate;SCHEMBL3078309;DTXSID20427371;QUYCPYFNAZEWOT-UHFFFAOYSA-N;AKOS024348896;p-Toluenesulfonic acid indan-2-yl ester;FT-0612647;EN300-7056798;2,3-dihydro-1H-inden-2-yl4-methylbenzenesulfonate;2,3-dihydro-1H-inden-2-yl 4-methylbenzene-1-sulfonate

Chemical Property of 2-Indanyl p-toluenesulfonate

Chemical Property:

• Vapor Pressure: 9.14E-08mmHg at 25°C
• Melting Point: 118-121°C
• Refractive Index: 1.622
• Boiling Point: 447.1°Cat760mmHg
• Flash Point: 224.2°C
• PSA: 51.75000
• Density: 1.29g/cm³
• LogP: 3.94850
• Sensitive.: Moisture Sensitive
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 288.08201554
• Heavy Atom Count: 20
• Complexity: 404

Purity/Quality:

99% ^*data from raw suppliers

2-IndanylP-Toluenesulfonate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC2CC3=CC=CC=C3C2

Technology Process of 2-Indanyl p-toluenesulfonate

There total 3 articles about 2-Indanyl p-toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

indan-2-ol (4254-29-9) + p-toluenesulfonyl chloride (98-59-9) → indan-2-yl p-toluenesulphonate (17783-69-6)

Guidance literature:

With trimethylamine hydrochloride; triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.1c02616

Reference yield:

1-bromo-indan-2-ol (52148-02-4) → indan-2-yl p-toluenesulphonate (17783-69-6)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) aq. KOH, EtOH, (ii) H₂, Raney-Ni

2: Py

With pyridine;

Reference yield:

→ indan-2-yl p-toluenesulphonate (17783-69-6)

Guidance literature:

Indan-2-ol, p-Toluolsulfonylchlorid, Py.;

upstream raw materials:

indan-2-ol

p-toluenesulfonyl chloride

1-bromo-indan-2-ol

Downstream raw materials:

indan-2-yl methyl ether

toluene-4-sulfonic acid

1-indene

2-ethoxyindan

Refernces

• 1、 Menger, F. M.,Chow, J. F.,Kaiserman, H.,Vasquez, P. C.. "Directionality of Proton Transfer in Solutions. Three Systems of Known Angularity". . p. 4996 - 5002. Retrieved 2007/10/02.