trimethylamine-1-benzylborane

Base Information

• Chemical Name: trimethylamine-1-benzylborane
• CAS No.: 124287-34-9
• Molecular Formula: C₁₀H₁₈BN
• Molecular Weight: 163.071
• Mol file: 124287-34-9.mol

Synonyms:trimethylamine-1-benzylborane

Chemical Property of trimethylamine-1-benzylborane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trimethylamine-1-benzylborane

There total 4 articles about trimethylamine-1-benzylborane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

trimethylamine-borane (75-22-9) + benzaldehyde p-toluenesulfonylhydrazone (1666-17-7) → trimethylamine-1-benzylborane (124287-34-9)

Guidance literature:

With rhodium(II) pivalate; lithium tert-butoxide; In 1,2-dichloro-ethane; at 55 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1021/jacs.8b05946

Reference yield: 75.0%

→ trimethylamine-1-benzylborane (124287-34-9)

Guidance literature:

With rhodium(II) pivalate; lithium tert-butoxide; In 1,2-dichloro-ethane; at 55 ℃; for 4h; Glovebox;

Reference yield:

toluene-4-sulfonic acid hydrazide (1576-35-8) → trimethylamine-1-benzylborane (124287-34-9)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 60 °C / Schlenk technique

2: lithium tert-butoxide; rhodium(II) pivalate / 1,2-dichloro-ethane / 4 h / 55 °C / Inert atmosphere; Schlenk technique

With rhodium(II) pivalate; lithium tert-butoxide; In methanol; 1,2-dichloro-ethane;

DOI:10.1021/jacs.8b05946

upstream raw materials:

trimethylamine-borane

trimethylamine hydrochloride

benzaldehyde p-toluenesulfonylhydrazone

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

2-benzyl-2,3-dihydro-1H-benzo[1,3,2]diazaborole

trimethylamine

Refernces

• 1、 -. "alpha-aryl or alkyl substituted borane adduct, preparation method and applications thereof". Paragraph 0103-0105; 0106; 0191-0193. . Retrieved 2020/01/25.