2-METHYL-4-PIPERIDINONE HYDROCHLORIDE

Base Information

• Chemical Name: 2-METHYL-4-PIPERIDINONE HYDROCHLORIDE
• CAS No.: 13729-77-6
• Molecular Formula: C₆H₁₁NO*ClH
• Molecular Weight: 149.62
• Hs Code.: 2933399990
• Mol file: 13729-77-6.mol

Synonyms:4-Piperidinone,2-methyl-, hydrochloride (9CI);4-Piperidone, 2-methyl-, hydrochloride (8CI);2-Methylpiperidin-4-one hydrochloride;2-Methyl-4-piperidone hydrochloride;

Chemical Property of 2-METHYL-4-PIPERIDINONE HYDROCHLORIDE

Chemical Property:

• PSA: 29.10000
• LogP: 1.45820
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2-Methylpiperidin-4-onehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-4-PIPERIDINONE HYDROCHLORIDE

There total 1 articles about 2-METHYL-4-PIPERIDINONE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-2-methylpiperidin-4-one acetic acid salt (790667-48-0) → (S)-2-methylpiperidin-4-one hydrochloride (790667-45-7,13729-77-6,1434126-97-2)

Guidance literature:

With hydrogenchloride; In water; isopropyl alcohol; toluene;

Reference yield: 95.0%

(S)-2-methylpiperidin-4-one hydrochloride (790667-45-7,13729-77-6,1434126-97-2) + di-tert-butyl dicarbonate (24424-99-5) → (S)-2-methyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester (790667-49-1)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃;

Reference yield: 93.0%

2-methyl-piperidin-4-one hydrochloride (13729-77-6,1434126-97-2) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 2-methyl-4-oxopiperidine-1-carboxylate (190906-92-4)

Guidance literature:

With dmap; In tetrahydrofuran; at 0 ℃; for 2h;

upstream raw materials:

(S)-2-methylpiperidin-4-one acetic acid salt

Downstream raw materials:

tert-butyl 2-methyl-4-oxopiperidine-1-carboxylate

(S)-2-methyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester

2-methyl-1-tosylpiperidin-4-one

3-bromo-2-methyl-1-tosylpiperidin-4-one

Refernces