8-Nonen-1-ol

Base Information

• Chemical Name: 8-Nonen-1-ol
• CAS No.: 13038-21-6
• Molecular Formula: C9H18O
• Molecular Weight: 142.241
• Hs Code.: 2905290000
• European Community (EC) Number: 848-942-9
• DSSTox Substance ID: DTXSID20454905
• Nikkaji Number: J112.180D
• Wikidata: Q82276706
• Mol file: 13038-21-6.mol

Synonyms:8-Nonen-1-ol;13038-21-6;Non-8-en-1-ol;8-nonenol;8-nonene-1-ol;SCHEMBL133624;DTXSID20454905;FKGFCVJJLGSFSB-UHFFFAOYSA-N;MFCD00798062;AKOS015839898;HY-W127362;AS-56400;CS-0185599;FT-0729302;N0650;D91757;EN300-210991;A930024;1-(5-NITROFURFURYLIDENE)AMINOGUANIDINEHYDROCHLORIDE

Chemical Property of 8-Nonen-1-ol

Chemical Property:

• Vapor Pressure: 0.094mmHg at 25°C
• Melting Point: -7°C (estimate)
• Refractive Index: 1.443
• Boiling Point: 197.948 °C at 760 mmHg
• PKA: 15.20±0.10(Predicted)
• Flash Point: 78.969 °C
• PSA: 20.23000
• Density: 0.838 g/cm³
• LogP: 2.50530
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 7
• Exact Mass: 142.135765193
• Heavy Atom Count: 10
• Complexity: 69.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

8-Nonen-1-ol ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCCCCCCCO
• Uses: 8-Nonen-1-ol is a reactant in the synthesis of chlorosulfolipid (+)-danicalipin A, which has cytotoxicity towards various mammalian cell lines and increases the uptake of fluorophores into bacteria and mammalian cells.

Technology Process of 8-Nonen-1-ol

There total 26 articles about 8-Nonen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

dibutyl ditelluride (77129-69-2) + 8-nonyn-1-ol (10160-28-8) → non-8-en-1-ol (13038-21-6)

Guidance literature:

dibutyl ditelluride; 8-nonyn-1-ol; With sodium tetrahydroborate; In ethanol;

With n-butyllithium; ammonium chloride; In tetrahydrofuran;

DOI:10.1016/S0040-4039(99)01967-X

Reference yield: 94.0%

8-nonyn-1-ol (10160-28-8) → non-8-en-1-ol (13038-21-6)

Guidance literature:

With hydrogen; Lindlar's catalyst; In methanol; for 0.75h;

DOI:10.1016/S0040-4039(00)61423-5

Reference yield: 87.0%

1-(tert-butyldimethylsilyloxy)non-8-ene (130252-79-8) → non-8-en-1-ol (13038-21-6)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2013.05.029

upstream raw materials:

2-non-8-enyloxy-tetrahydro-pyran

9-hydroxy-2-nonanone

non-8-enoic acid

ethyl non-8-enoate

Downstream raw materials:

non-8-en-1-yl acetate

1-bromo-9-(4,4,5,5,5-pentafluoropentylsulfanyl)nonane

9-hydroxy-2-nonanone

2-(pent-4-en-1-yl)tetrahydrofuran

Refernces

• 1、 Hirosawa, Keishi,Mashima, Kazushi,Satoh, Tetsuya,Shinohara, Koichi,Shirase, Satoru,Tamaki, Sota,Tsurugi, Hayato. "Cerium(IV) Carboxylate Photocatalyst for Catalytic Radical Formation from Carboxylic Acids: Decarboxylative Oxygenation of Aliphatic Carboxylic Acids and Lactonization of Aromatic Carboxylic Acids". supporting information. . Retrieved 2020/03/25.
• 2、 Sato, Takuya,Joh, Yohei,Oishi, Tohru,Torikai, Kohei. "1-Naphthylmethyl and 1-naphthylmethoxymethyl protecting groups: New members of the benzyl- and benzyloxymethyl-type family". supporting information. p. 2178 - 2181. Retrieved 2017/05/16.