C₂₅H₃₂BrNO₄

Base Information

• Chemical Name: C₂₅H₃₂BrNO₄
• CAS No.: 1390665-75-4
• Molecular Formula: C₂₅H₃₂BrNO₄
• Molecular Weight: 490.437
• Mol file: 1390665-75-4.mol

Synonyms:C₂₅H₃₂BrNO₄

Chemical Property of C₂₅H₃₂BrNO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₂BrNO₄

There total 4 articles about C₂₅H₃₂BrNO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C18H29NO3 (1390665-79-8) + 4-chlorobenzoyl chloride (586-75-4) → C25H32BrNO4 (1390665-75-4)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 12h; Cooling with ice;

DOI:10.1016/j.bmcl.2012.05.124

Reference yield:

3-(5-ethoxycarbonylpentyloxy)benzaldehyde (1234918-43-4) → C25H32BrNO4 (1390665-75-4)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride / water; toluene / Reflux

2: sodium cyanoborohydride / ethanol / 20 °C / Cooling with ice

3: dmap; triethylamine / dichloromethane / 12 h / 20 °C / Cooling with ice

With hydrogenchloride; dmap; sodium cyanoborohydride; triethylamine; In ethanol; dichloromethane; water; toluene;

DOI:10.1016/j.bmcl.2012.05.124

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → C25H32BrNO4 (1390665-75-4)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 24 h / Inert atmosphere; Reflux

2: hydrogenchloride / water; toluene / Reflux

3: sodium cyanoborohydride / ethanol / 20 °C / Cooling with ice

4: dmap; triethylamine / dichloromethane / 12 h / 20 °C / Cooling with ice

With hydrogenchloride; dmap; sodium cyanoborohydride; potassium carbonate; triethylamine; In ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; 1: Williamson etherification;

DOI:10.1016/j.bmcl.2012.05.124

upstream raw materials:

3-(5-ethoxycarbonylpentyloxy)benzaldehyde

C₁₈H₂₉NO₃

4-chlorobenzoyl chloride

meta-hydroxybenzaldehyde

Downstream raw materials:

C₃₉H₄₂N₂O₆S

C₃₃H₄₂N₂O₄

C₂₉H₃₅NO₅

C₂₉H₃₅NO₄S

Refernces