Methyl L-ornithine dihydrochloride

Base Information

• Chemical Name: Methyl L-ornithine dihydrochloride
• CAS No.: 40216-82-8
• Molecular Formula: C₆H₁₄N₂O₂*2ClH
• Molecular Weight: 219.111
• Hs Code.: 2922499990
• Mol file: 40216-82-8.mol

Synonyms:L-Ornithine, methyl ester, dihydrochloride(9CI);Ornithine, methyl ester, dihydrochloride,L- (7CI);H-Orn-Ome·2HCl;H-Orn-OMec2HCl;

Chemical Property of Methyl L-ornithine dihydrochloride

Chemical Property:

• Vapor Pressure: 0.000816mmHg at 25°C
• Boiling Point: 300.9 °C at 760 mmHg
• Flash Point: 135.8 °C
• PSA: 78.34000
• LogP: 2.23020
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

H-Orn-OMeDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl L-ornithine dihydrochloride

There total 7 articles about Methyl L-ornithine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + L-ornithine hydrochloride (3184-13-2,36630-89-4) → methyl (S)-2,5-diaminopentanoate dihydrochloride (40216-82-8,60080-69-5)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃; for 22h;

DOI:10.1021/np030491b

Reference yield:

L-ornithine hydrochloride (3184-13-2,36630-89-4) → methyl (S)-2,5-diaminopentanoate dihydrochloride (40216-82-8,60080-69-5)

Guidance literature:

With thionyl chloride; In methanol;

Reference yield:

L-ornithine monohydrate (207734-73-4) + di-isopropyl ether (108-20-3) → methyl (S)-2,5-diaminopentanoate dihydrochloride (40216-82-8,60080-69-5)

Guidance literature:

With thionyl chloride; In methanol;

upstream raw materials:

L-ornithine hydrochloride

methanol

L-ornithine monohydrate

di-isopropyl ether

Downstream raw materials:

(-)-2,3-dibenzyloxybenzoyl-L-Orn(2,3-dibenzyloxybenzoyl)-NH₂

(3S)--3-aminopiperidine

(3S)--3-(methylamino)piperidine

Refernces

• 1、 -. "ANTI-INFLAMMATORY COMPOSITION". Page/Page column 13-14. . Retrieved 2009/03/07.
• 2、 Abe, Masatoshi,Akiyama, Tetsuo,Nakamura, Hikaru,Kojima, Fukiko,Harada, Shigeko,Muraoka, Yasuhiko. "First synthesis and determination of the absolute configuration of sulphostin, a novel inhibitor of dipeptidyl peptidase IV". . p. 999 - 1004. Retrieved 2007/10/03.