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(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide

Base Information Edit
  • Chemical Name:(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide
  • CAS No.:378236-67-0
  • Molecular Formula:C10H7F2N3O
  • Molecular Weight:223.182
  • Hs Code.:
  • Mol file:378236-67-0.mol
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide

Synonyms:(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide

Suppliers and Price of (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonylAzide
  • 5mg
  • $ 185.00
Total 5 raw suppliers
Chemical Property of (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide Edit
Chemical Property:
Purity/Quality:

98% *data from raw suppliers

(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonylAzide *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Uses (1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonyl Azide is a useful synthetic intermediate in the synthesis of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is also used in the treatment of acute coronary syndromes (ACS).
Technology Process of (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide

There total 6 articles about (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With acetic acid; sodium nitrite; at 25 ℃; for 0.5h;
Guidance literature:
With hydrogenchloride; sodium azide; In water; acetone; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1002/anie.201814123
Guidance literature:
trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid; chloroformic acid ethyl ester; With TEA; In acetone;
With sodium azide; In water; Further stages.;
DOI:10.1016/j.bmcl.2007.07.057
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