2-IODOSTYRENE

Base Information

• Chemical Name: 2-IODOSTYRENE
• CAS No.: 4840-91-9
• Molecular Formula: C8H7 I
• Molecular Weight: 230.048
• Hs Code.: 2903998090
• Mol file: 4840-91-9.mol

Synonyms:Styrene,o-iodo- (7CI,8CI); 2-Iodostyrene

Chemical Property of 2-IODOSTYRENE

Chemical Property:

• Boiling Point: 88-90 °C(Press: 3 Torr)
• PSA: 0.00000
• Density: 1.6734 g/cm3
• LogP: 2.93420
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

2-Iodostyrene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-IODOSTYRENE

There total 17 articles about 2-IODOSTYRENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-iodobenzyl alcohol (5159-41-1) → o-iodostyrene (4840-91-9)

Guidance literature:

2-iodobenzyl alcohol; With triethylphosphine hydrobromide; at 100 ℃; for 0.166667h; Microwave irradiation;

formaldehyd; With potassium carbonate; In water; at 100 ℃; for 0.0833333h; Microwave irradiation;

DOI:10.1080/10426507.2014.980907

Reference yield: 95.0%

2-iodobenzaldehyde (26260-02-6) + Methyltriphenylphosphonium bromide (1779-49-3) → o-iodostyrene (4840-91-9)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 3h;

DOI:10.1016/j.tet.2012.06.001

Reference yield: 79.0%

-butyl vinyl ether (111-34-2,92680-80-3) + phenyllithium (591-51-5) → o-iodostyrene (4840-91-9)

Guidance literature:

-butyl vinyl ether; phenyllithium; With zirconocene methyl chloride; In tetrahydrofuran; at -78 - 80 ℃; for 3.5h;

With iodine; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1055/s-2005-872699

upstream raw materials:

2-iodo-α-methyl-benzenemethanol

2-iodobenzaldehyde

Methyltriphenylphosphonium bromide

2-Iodobenzoyl chloride

Downstream raw materials:

2-(2-iodophenyl)oxirane

1-(2-iodo-pheyl)-hex-5-en-1-ol

2-Iodobenzoic acid

Refernces

• 1、 Puleo, Thomas R.,Strong, Alivia J.,Bandar, Jeffrey S.. "Catalytic α-Selective Deuteration of Styrene Derivatives". supporting information. p. 1467 - 1472. Retrieved 2019/01/25.
• 2、 Lee, Yong Ho,Morandi, Bill. "Metathesis-active ligands enable a catalytic functional group metathesis between aroyl chlorides and aryl iodides". . p. 1016 - 1022. Retrieved 2018/09/06.