2-Deoxy-D-arabino-hexose 6-(dihydrogen phosphate)

Base Information

• Chemical Name: 2-Deoxy-D-arabino-hexose 6-(dihydrogen phosphate)
• CAS No.: 3573-50-0
• Molecular Formula: C₆H₁₃O₈P
• Molecular Weight: 244.138
• UNII: ZFR70WJ2SL
• DSSTox Substance ID: DTXSID40957140
• Nikkaji Number: J579.201K
• Wikidata: Q27098347
• Mol file: 3573-50-0.mol

Synonyms:2-deoxyglucose-6-phosphate

Chemical Property of 2-Deoxy-D-arabino-hexose 6-(dihydrogen phosphate)

Chemical Property:

• Refractive Index: 1.574
• Boiling Point: 606.9°Cat760mmHg
• PKA: 1.84±0.10(Predicted)
• Flash Point: 320.8°C
• PSA: 146.49000
• Density: 1.694g/cm³
• LogP: -2.07520
• XLogP3: -4
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 7
• Exact Mass: 244.03480437
• Heavy Atom Count: 15
• Complexity: 237

Purity/Quality:

99%min ^*data from raw suppliers

2-Deoxy-D-glucose-6-phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C=O)C(C(C(COP(=O)(O)O)O)O)O
• Isomeric SMILES: C(C=O)[C@H]([C@@H]([C@@H](COP(=O)(O)O)O)O)O

Technology Process of 2-Deoxy-D-arabino-hexose 6-(dihydrogen phosphate)

There total 5 articles about 2-Deoxy-D-arabino-hexose 6-(dihydrogen phosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-deoxy-D-galactose (1949-89-9) → O6-phosphono-D-lyxo-2-deoxy-hexose (3573-50-0,13004-81-4,65206-74-8,5511-93-3)

Guidance literature:

Multi-step reaction with 5 steps

1: hydrogen chloride

2: zinc chloride

3: pyridine

4: platinum; aqueous methanol / Hydrogenation

5: aqueous sulfuric acid

With pyridine; hydrogenchloride; methanol; sulfuric acid; platinum; zinc(II) chloride;

Reference yield:

methyl 2-deoxy-α-D-galactopyranoside (3971-45-7) → O6-phosphono-D-lyxo-2-deoxy-hexose (3573-50-0,13004-81-4,65206-74-8,5511-93-3)

Guidance literature:

Multi-step reaction with 4 steps

1: zinc chloride

2: pyridine

3: platinum; aqueous methanol / Hydrogenation

4: aqueous sulfuric acid

With pyridine; methanol; sulfuric acid; platinum; zinc(II) chloride;

Reference yield:

methyl 2-deoxy-3,4-O-isopropylidene-α-D-lyxo-hexopyranoside (146669-00-3) → O6-phosphono-D-lyxo-2-deoxy-hexose (3573-50-0,13004-81-4,65206-74-8,5511-93-3)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine

2: platinum; aqueous methanol / Hydrogenation

3: aqueous sulfuric acid

With pyridine; methanol; sulfuric acid; platinum;

upstream raw materials:

methyl-(O³,O⁴-isopropylidene-O⁶-phosphono-α-D-lyxo-2-deoxy-hexopyranoside)

2-deoxy-D-galactose

methyl 2-deoxy-α-D-galactopyranoside

methyl 2-deoxy-3,4-O-isopropylidene-α-D-lyxo-hexopyranoside