diphenyl(β-chloroethyl)phosphine oxide

Base Information

• Chemical Name: diphenyl(β-chloroethyl)phosphine oxide
• CAS No.: 13172-83-3
• Molecular Formula: C₁₄H₁₄ClOP
• Molecular Weight: 264.691
• Mol file: 13172-83-3.mol

Synonyms:diphenyl(β-chloroethyl)phosphine oxide

Chemical Property of diphenyl(β-chloroethyl)phosphine oxide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diphenyl(β-chloroethyl)phosphine oxide

There total 13 articles about diphenyl(β-chloroethyl)phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

vinyldiphenylphosphine oxide (2096-78-8) → diphenyl(β-chloroethyl)phosphine oxide (13172-83-3)

Guidance literature:

With hydrogenchloride; at 125 - 130 ℃; for 2h;

Reference yield: 71.0%

oxirane (75-21-8,99932-75-9) + (-)-menthyl chloroacetate (7377-98-2,27994-88-3,88644-14-8,106916-72-7,111957-92-7,21758-29-2) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → menthyl diphenylphosphorylacetate + diphenyl(β-chloroethyl)phosphine oxide (13172-83-3)

Guidance literature:

In benzene; at 5 - 125 ℃;

DOI:10.1007/s11172-007-0047-7

Reference yield: 67.0%

2-(diphenylphosphinyl)ethanol (887-21-8) → diphenyl(β-chloroethyl)phosphine oxide (13172-83-3)

Guidance literature:

With triethylamine; trichlorophosphate; In toluene; at 65 - 70 ℃; for 3h;

upstream raw materials:

2-(diphenylphosphinyl)ethanol

Bis-chlormethyl-diphenyl-phosphoniumchlorid

β-chloroethyl diphenylphosphite

vinyldiphenylphosphine oxide

Downstream raw materials:

1,2-bis(diphenylphosphinoyl)ethane

2-(diphenylphosphinyl)ethylphosphonic acid diethyl ester

vinyldiphenylphosphine oxide

C₂₂H₃₂O₂P₂

Refernces

• 1、 Bredikhin,Eliseenkova,Tarasova,Voskresenskaya,Balandina,Dobrynin,Latypov,Litvinov,Sharafutdinova,Efremov. "Nonracemic menthyl phosphorylacetates". . p. 290 - 297. Retrieved 2008/03/12.
• 2、 Bondarenko, N. A.,Tsvetkov, E. N.. "SYNTHESIS OF VINYLDIPHENYLPHOSPHINE OXIDE FROM DIPHENYLPHOSPHONOUS ACID". . p. 1361 - 1364. Retrieved 2007/10/02.