Technology Process of 2,6-bis(4-methoxyphenyl)-1-methylpiperidin-4-one O-4-hydroxybenzoyloxime
There total 4 articles about 2,6-bis(4-methoxyphenyl)-1-methylpiperidin-4-one O-4-hydroxybenzoyloxime which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2,6-bis(4-methoxyphenyl)-1-methylpiperidin-4-one oxime;
With
potassium tert-butylate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.416667h;
4-hydroxybenzoyl chloride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 8h;
DOI:10.1007/s00044-013-0793-z
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: ammonium acetate / ethanol / Heating
2.1: potassium carbonate / acetone / 4 h / Reflux
3.1: sodium acetate trihydrate / ethanol / 0.25 h / Heating
3.2: 2 h / Reflux
4.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.42 h / 20 °C
4.2: 8 h / 20 °C
With
potassium tert-butylate; ammonium acetate; sodium acetate trihydrate; potassium carbonate;
In
ethanol; N,N-dimethyl-formamide; acetone;
1.1: |Mannich Aminomethylation;
DOI:10.1007/s00044-013-0793-z
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / acetone / 4 h / Reflux
2.1: sodium acetate trihydrate / ethanol / 0.25 h / Heating
2.2: 2 h / Reflux
3.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.42 h / 20 °C
3.2: 8 h / 20 °C
With
potassium tert-butylate; sodium acetate trihydrate; potassium carbonate;
In
ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1007/s00044-013-0793-z