7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[E][1,4]diazepine-2,5-dione

Base Information Edit

Chemical Name:7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[E][1,4]diazepine-2,5-dione
CAS No.:78755-80-3
Molecular Formula:C10H9FN2O2
Molecular Weight:208.192
Hs Code.:2933990090
European Community (EC) Number:811-382-0
UNII:5JJ4V0H2YN
DSSTox Substance ID:DTXSID30349737
Nikkaji Number:J1.880.039J
Wikidata:Q72479682
ChEMBL ID:CHEMBL1575282
Mol file:78755-80-3.mol

Synonyms:78755-80-3;7-FLUORO-4-METHYL-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE;7-FLUORO-3,4-DIHYDRO-4-METHYL-1H-1,4-BENZODIAZEPINE-2,5-DIONE;7-fluoro-4-methyl-1,3-dihydro-1,4-benzodiazepine-2,5-dione;Flumazenil dione;1H-1,4-Benzodiazepine-2,5-dione, 7-fluoro-3,4-dihydro-4-methyl-;5JJ4V0H2YN;7-fluoro-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione;7-Fluoro-4-methyl-3,4-dihydro-1H-benzo(E)(1,4)diazepine-2,5-dione;SMR000039984;Flumazenil dione [USP];UNII-5JJ4V0H2YN;3,4-DIHYDRO-7-FLUORO-4-METHYL-2H-1,4-BENZODIAZEPINE-2,5(1H)-DIONE;Oprea1_806073;Oprea1_869834;MLS000069257;SCHEMBL7138979;CHEMBL1575282;DTXSID30349737;BKHGZIQXTHAVNJ-UHFFFAOYSA-N;HMS2368O12;MFCD01063090;STK824460;7-FLUORO-3,4-DIHYDRO-4-METHYL-2H-1,4-BENZODIAZEPINE-2,5(1H)-DIONE;AKOS001609422;FLUMAZENIL DIONE [USP IMPURITY];NCGC00018768-01;NCGC00018768-02;AC-26328;AS-35921;FLUMAZENIL IMPURITY D [EP IMPURITY];CS-0085139;FT-0659462;A839483;SR-01000000723;SR-01000000723-2

Suppliers and Price of 7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[E][1,4]diazepine-2,5-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
500mg
$ 1470.00

TRC
7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
50mg
$ 185.00

TRC
7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
10 mg
$ 115.00

SynQuest Laboratories
3,4-Dihydro-7-fluoro-4-methyl-2H-1,4-benzodiazepine-2,5(1H)-dione 97%
1 g
$ 288.00

Crysdot
7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 95+%
1g
$ 210.00

Crysdot
7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 95+%
10g
$ 860.00

Crysdot
7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 95+%
5g
$ 540.00

Chemenu
7-fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 95%
5g
$ 505.00

Chemenu
7-fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 95%
10g
$ 804.00

AstaTech
7-FLUORO-4-METHYL-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE 97%
1 / G
$ 782.00

Total 42 raw suppliers

Chemical Property of 7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[E][1,4]diazepine-2,5-dione Edit

Chemical Property:

Boiling Point:434.5 °C at 760 mmHg
PKA:12.02±0.20(Predicted)
Flash Point:216.6 °C
PSA：52.90000
Density:1.345 g/cm³
LogP:0.87280
Storage Temp.:2-8°C
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:208.06480570
Heavy Atom Count:15
Complexity:295

Purity/Quality:

99% ^*data from raw suppliers

7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CC(=O)NC2=C(C1=O)C=C(C=C2)F
Uses 7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione, is used as a reactant in the synthetic preparation of 18F-labeled radiotracers for γ-aminobutyric acid A (GABAA) receptor positron emission tomography (PET) imaging.

Technology Process of 7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[E][1,4]diazepine-2,5-dione

There total 7 articles about 7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[E][1,4]diazepine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%