Isopropyldimethylchlorosilane

Base Information

• Chemical Name: Isopropyldimethylchlorosilane
• CAS No.: 3634-56-8
• Molecular Formula: C5H13ClSi
• Molecular Weight: 136.697
• Hs Code.: 29319090
• European Community (EC) Number: 628-530-3
• DSSTox Substance ID: DTXSID10408351
• Nikkaji Number: J208.379E
• Wikidata: Q82213817
• Mol file: 3634-56-8.mol

Synonyms:3634-56-8;Isopropyldimethylchlorosilane;Chloro(dimethyl)isopropylsilane;Dimethylisopropylchlorosilane;chloro-dimethyl-propan-2-ylsilane;chloro(isopropyl)dimethylsilane;Chloro-isopropyl-dimethylsilane;dimethyl isopropyl silyl chloride;chlorodimethyl(propan-2-yl)silane;DMIPSCl;Chlorodimethylisopropylsilane;Silane, chlorodimethyl(1-methylethyl)-;Isopropyldmethylchlorosilane;chlorodimethyl isopropylsilane;SCHEMBL523409;dimethyl-isopropyl-silylchloride;chloro-isopropyl-dimethyl-silane;DTXSID10408351;YCXVDEMHEKQQCI-UHFFFAOYSA-N;AMY42251;MFCD00009917;Chloro(dimethyl)isopropylsilane, 97%;AKOS015915869;AS-49524;D1594;FT-0634940;I11233;EN300-7464658

Chemical Property of Isopropyldimethylchlorosilane

Chemical Property:

• Vapor Pressure: 29.4mmHg at 25°C
• Refractive Index: n20/D 1.416
• Boiling Point: 109.2 °C at 760 mmHg
• Flash Point: 15 °C
• PSA: 0.00000
• Density: 0.862 g/cm³
• LogP: 2.84030
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 136.0475046
• Heavy Atom Count: 7
• Complexity: 59.1

Purity/Quality:

98% ^*data from raw suppliers

Dimethylisopropylchlorosilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F; C
• Hazard Codes: F,C
• Statements: 11-34-37
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C)[Si](C)(C)Cl

Technology Process of Isopropyldimethylchlorosilane

There total 2 articles about Isopropyldimethylchlorosilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aluminium trichloride (7446-70-0) + (1-chloroethyl)trimethylsilane (7787-87-3) → chloro-trimethyl-silane (75-77-4) + ethene (74-85-1) + isopropyldimethylsilyl chloride (3634-56-8)

Guidance literature:

DOI:10.1021/ja01632a050

Reference yield:

(1-chloroethyl)trimethylsilane (7787-87-3) → chloro-trimethyl-silane (75-77-4) + isopropyldimethylsilyl chloride (3634-56-8)

Guidance literature:

With aluminium trichloride;

DOI:10.1021/ja01632a050

Reference yield: 99.0%

isopropyldimethylsilyl chloride (3634-56-8) + (3R,4R,5S,1'R)-3-[N-(benzyloxycarbonyl)amino]-5-(1-hydroxyethyl)-4-methoxytetrahydrofuran-2-one (182216-97-3) → (3R,4R,5S,1'R)-3-[N-(benzyloxycarbonyl)amino]-5-[1-(isopropyldimethylsilanyloxy)ethyl]-4-methoxytetrahydrofuran-2-one (182216-98-4)

Guidance literature:

With 1H-imidazole; In tetrahydrofuran; for 1h; Ambient temperature;

DOI:10.1016/0040-4039(96)01173-2

upstream raw materials:

(1-chloroethyl)trimethylsilane

aluminium trichloride

Downstream raw materials:

2,2,3-trimethyl-2-silabutane

(+/-)-3r-isopropyldimethylsiloxy-6c-phthalimidocyclohexene

(+/-)-3r-isopropyldimethylsiloxy-4t,5c-dimethoxy-6c-phthalimidocyclohexene

(1S,2R,3S,6R)-6-((benzyloxycarbonyl)amino)-1,2-O-isopropylidene-3-((isopropyldimethylsilyl)oxy)cyclohex-4-ene-1,2-diol