Technology Process of C46H50N8O8
There total 4 articles about C46H50N8O8 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; hydroxybenzotriazole hydrate; i-Pr2NEt / dimethylformamide
2: TFA / CH2Cl2
3: benzotriazol-1-yloxytris(dimethylamino)-phosphonium-PF6; hydroxybenzotriazole hydrate; i-Pr2NEt / dimethylformamide
4: piperidine
5: benzotriazol-1-yloxytris(dimethylamino)-phosphonium-PF6; hydroxybenzotriazole hydrate; i-Pr2NEt / dimethylformamide
With
piperidine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; N,N-dimethyl-formamide;
1: Acylation / 2: Deprotection / 3: Acylation / 4: Deprotection / 5: Acylation;
DOI:10.1016/S0960-894X(00)00036-6
- Guidance literature:
-
Multi-step reaction with 3 steps
1: benzotriazol-1-yloxytris(dimethylamino)-phosphonium-PF6; hydroxybenzotriazole hydrate; i-Pr2NEt / dimethylformamide
2: piperidine
3: benzotriazol-1-yloxytris(dimethylamino)-phosphonium-PF6; hydroxybenzotriazole hydrate; i-Pr2NEt / dimethylformamide
With
piperidine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
1: Acylation / 2: Deprotection / 3: Acylation;
DOI:10.1016/S0960-894X(00)00036-6
- Guidance literature:
-
Multi-step reaction with 4 steps
1: TFA / CH2Cl2
2: benzotriazol-1-yloxytris(dimethylamino)-phosphonium-PF6; hydroxybenzotriazole hydrate; i-Pr2NEt / dimethylformamide
3: piperidine
4: benzotriazol-1-yloxytris(dimethylamino)-phosphonium-PF6; hydroxybenzotriazole hydrate; i-Pr2NEt / dimethylformamide
With
piperidine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; N,N-dimethyl-formamide;
1: Deprotection / 2: Acylation / 3: Deprotection / 4: Acylation;
DOI:10.1016/S0960-894X(00)00036-6