1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide

Base Information

• Chemical Name: 1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide
• CAS No.: 101737-97-7
• Molecular Formula: C₁₈H₂₄N₂O₃
• Molecular Weight: 316.4
• Mol file: 101737-97-7.mol

Synonyms:

Chemical Property of 1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide

There total 5 articles about 1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-methyl ester (4652-65-7) → 1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide (101737-97-7)

Guidance literature:

Multi-step reaction with 3 steps

1: PCl₅

2: palladium; aqueous methanol. acetic acid / Hydrogenation

With phosphorus pentachloride; palladium; acetic acid;

Reference yield:

methyl (4S)-5-oxo-4-[[(phenylmethoxy)carbonyl]amino]-5-[(2-phenylethyl)amino]pentanoate (121426-39-9) → 1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide (101737-97-7)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium; aqueous methanol. acetic acid / Hydrogenation

With palladium; acetic acid;

Reference yield:

phenethylamine (64-04-0) → 1-((S)-2-methyl-butyryl)-5-oxo-L-proline-phenethylamide (101737-97-7)

Guidance literature:

Multi-step reaction with 3 steps

1: PCl₅

2: palladium; aqueous methanol. acetic acid / Hydrogenation

With phosphorus pentachloride; palladium; acetic acid;

upstream raw materials:

pyridine

(S)-2-methylbutanoyl chloride

5-oxo-L-proline-phenethylamide

(S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-methyl ester

Downstream raw materials:

N²-((S)-2-methyl-butyryl)-N⁵-phenethyl-L-glutamine