Dimethylphosphinic acid

Base Information

• Chemical Name: Dimethylphosphinic acid
• CAS No.: 3283-12-3
• Molecular Formula: C2H7 O2 P
• Molecular Weight: 94.0501
• Hs Code.: 2915900090
• European Community (EC) Number: 221-927-9
• UNII: HWF42NF4CG
• DSSTox Substance ID: DTXSID00186499
• Nikkaji Number: J21.046C
• Wikidata: Q27109816
• Metabolomics Workbench ID: 53920
• Mol file: 3283-12-3.mol

Synonyms:Dimethylphosphinic acid;3283-12-3;Dimethylphosphinicacid;HWF42NF4CG;16391-06-3;MFCD00009611;UNII-HWF42NF4CG;DimethylphosphinsA currencyure;Dimethylphosphinic acid, 97%;CHEBI:23814;GOJNABIZVJCYFL-UHFFFAOYSA-;DTXSID00186499;P,P-DIMETHYLPHOSPHINIC ACID;EINECS 221-927-9;HYDROXYDIMETHYLPHOSPHINE OXIDE;AKOS015892871;PHOSPHINIC ACID, P,P-DIMETHYL-;AS-58057;FT-0739345;J-018899;Q27109816

Chemical Property of Dimethylphosphinic acid

Chemical Property:

• Vapor Pressure: 67.604mmHg at 25°C
• Melting Point: 85-89 °C(lit.)
• Boiling Point: 277°Cat760mmHg
• PKA: 2.90±0.50(Predicted)
• Flash Point: 137.7°C
• PSA: 47.11000
• Density: 1.13g/cm³
• LogP: 0.51640
• XLogP3: -1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 94.01836646
• Heavy Atom Count: 5
• Complexity: 62

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dimethylphosphinic acid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CP(=O)(C)O
• Uses: Dimethylphosphinic acid was used in preparation of microcrystalline organometallic coordination polymer.

Technology Process of Dimethylphosphinic acid

There total 23 articles about Dimethylphosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

bis(trimethylsilyl)phosphonite (30148-50-6) + methyl iodide (74-88-4) → dimethylphosphinic acid (3283-12-3) + methylphosphinic acid (4206-94-4)

Guidance literature:

bis(trimethylsilyl)phosphonite; methyl iodide; In dichloromethane; at 0 - 20 ℃; for 14h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 0 - 20 ℃; for 2h;

DOI:10.1039/c2ob26395e

Reference yield: 74.5%

dimethyldiiodophosphonium triiodide → dimethylphosphinic acid (3283-12-3)

Guidance literature:

With water; Heating;

Reference yield: 40.1%

dimethyldiiodophosphonium iodide → dimethylphosphinic acid (3283-12-3)

Guidance literature:

With water; iodine; Heating;

upstream raw materials:

tetramethyl-diphosphine disulphide

dimethylphosphane

dimethyl-phosphinic acid-anhydride

dimethyl methylthiophosphinite

Downstream raw materials:

[Fe₂(N,N,N′,N′-tetrakis((1-ethylbenzimidazol-2-yl)methyl)-2-hydroxy-1,3-diaminopropane(-1H))(μ-dimethylphosphinate)](BPh₄)(OTf)

[4-({[2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5-(2-thienyl)phenyl]amino}carbonyl)phenyl] methyl dimethylphosphinate

(hydroxy{[(dimethyl)phosphoryl]oxy}iodo)benzene

dimethylphosphinic acid chloride

Refernces

• 1、 Nakamoto et al.. "". . p. 521. Retrieved 1969.
• 2、 Markoulides, Marios S.,Regan, Andrew C.. "Synthesis of a phosphinate analogue of the anti-tumour phosphate di-ester perifosine via sequential radical processes". . p. 119 - 129. Retrieved 2013/02/23.
• 3、 -. "Phosphorus-containing compounds and uses thereof". . . Retrieved 2008/06/13.