Benzenamine, 4-fluoro-N-propyl-

Base Information

• Chemical Name: Benzenamine, 4-fluoro-N-propyl-
• CAS No.: 2806-12-4
• Molecular Formula: C9H12FN
• Molecular Weight: 153.199
• Mol file: 2806-12-4.mol

Synonyms:4-fluoro-N-propylbenzenamine;4-Fluor-N-propyl-anilin;(4-Fluoro-phenyl)-propyl-amine;

Chemical Property of Benzenamine, 4-fluoro-N-propyl-

Chemical Property:

• PSA: 12.03000
• LogP: 2.72060

Purity/Quality:

95% ^*data from raw suppliers

Benzenamine,4-fluoro-N-propyl- 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenamine, 4-fluoro-N-propyl-

There total 6 articles about Benzenamine, 4-fluoro-N-propyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

p-azidofluorobenzene (3296-02-4) + n-propylmagnesium bromide (927-77-5) → 4-fluoro-N-propylaniline (2806-12-4)

Guidance literature:

In diethyl ether; at 20 ℃; for 1h;

DOI:10.1016/S0040-4039(99)01771-2

Reference yield: 71.0%

ethene (74-85-1) + 4-fluoro-N-methylaniline (459-59-6) → 4-fluoro-N-(pentan-3-yl)aniline + 4-fluoro-N-propylaniline (2806-12-4)

Guidance literature:

With C₃₁H₅₃N₅Ti; In toluene; at 160 ℃; for 24h; under 1064.07 Torr; Schlenk technique; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1002/chem.201904502

Reference yield: 40.0%

tri-n-propylamine (102-69-2) + 4-fluoroaniline (371-40-4) → 4-fluoro-N-propylaniline (2806-12-4)

Guidance literature:

With palladium 10% on activated carbon; In toluene; at 175 ℃; for 1.5h; Inert atmosphere; Microwave irradiation;

DOI:10.1002/chem.201002704

upstream raw materials:

p-azidofluorobenzene

n-propylmagnesium bromide

4-fluoroaniline

tri-n-propylamine

Downstream raw materials:

4-(fluorophenyl)propylcarbamic chloride

Refernces

• 1、 Lubinu, M. Caterina,De Luca, Lidia,Giacomelli, Giampaolo,Porcheddu, Andrea. "Microwave-promoted selective mono-n-alkylation of anilines with tertiary amines by heterogeneous catalysis". supporting information; experimental part. p. 82 - 85. Retrieved 2011/03/21.
• 2、 -. "Herbicidal oxadiazolidines". Page 18. . Retrieved 2010/11/30.