Zinc, chlorophenyl-

Base Information

• Chemical Name: Zinc, chlorophenyl-
• CAS No.: 28557-00-8
• Molecular Formula: C6H5ClZn
• Molecular Weight: 177.949
• Mol file: 28557-00-8.mol

Synonyms:

Chemical Property of Zinc, chlorophenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Zinc, chlorophenyl-

There total 15 articles about Zinc, chlorophenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylmagnesium bromide (100-58-3) + zinc(II) chloride (7646-85-7,24359-56-6) → phenylzinc chloride (28557-00-8) + diphenylzinc (1078-58-6)

Guidance literature:

In tetrahydrofuran; at -15 ℃; for 0.0833333h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2015.08.012

Reference yield:

bromobenzene (108-86-1,52753-63-6) + zinc(II) chloride (7646-85-7,24359-56-6) → phenylzinc chloride (28557-00-8)

Guidance literature:

bromobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Schlenk technique; Inert atmosphere;

zinc(II) chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c3cc44894k

Reference yield:

phenylmagnesium bromide (100-58-3) + zinc(II) chloride (7646-85-7,24359-56-6) → phenylzinc chloride (28557-00-8)

Guidance literature:

In tetrahydrofuran; (N2), 1 equiv. of PhMgBr in THF added to 1 equiv. of ZnCl2 in THF at -15°C, stirred for 5 min;

DOI:10.1016/j.jorganchem.2011.11.027

upstream raw materials:

phenylmagnesium chloride

zinc(II) chloride

phenyllithium

phenylmagnesium bromide

Downstream raw materials:

4-oxo-2.3-dimethyl-4-phenyl-cis-crotonic acid

2-(2,4-dimethylphenyl)-1-phenylethan-1-one

chloro-diphenylphosphine

2-phenylfuran

Refernces

• 1、 Chen, Jingjia,Hu, Weipeng,Jin, Jing,Lovinger, Gabriel J.,Morken, James P.,Zhang, Chenlong. "Enantiomerically Enriched α-Borylzinc Reagents by Nickel-Catalyzed Carbozincation of Vinylboronic Esters". supporting information. p. 14189 - 14195. Retrieved 2021/09/11.
• 2、 Hayashi, Tamio,Ng, Jia Sheng. "Asymmetric Synthesis of Fluorinated Allenes by Rhodium-Catalyzed Enantioselective Alkylation/Defluorination of Propargyl Difluorides with Alkylzincs". supporting information. p. 20771 - 20775. Retrieved 2021/08/25.