- Rifamycin AF/API
- Rifamycin O
- Rifamycin S
- Rifamycin sodium salt
- RIFAMYCIN SV
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Cas Database |
| Name |
RIFAMYCIN SV |
EINECS | 230-273-3 |
| CAS No. | 6998-60-3 | Density | 1.2275 (rough estimate) |
| PSA | 201.31000 | LogP | 4.89210 |
| Solubility | N/A | Melting Point |
300° (dec 140°) |
| Formula | C37H47 N O12 | Boiling Point | 701.9°C (rough estimate) |
| Molecular Weight | 697.78 | Flash Point | N/A |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione,5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-,21-acetate (8CI);Rifomycin SV (6CI);(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-(Acetyloxy)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione;2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione,21-(acetyloxy)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-,(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-;NSC 133100;Rifamicine SV;Rifampin SV;Rifamycin SV;Rifocin;Rifogal;Rifomycin;Riphogal;[2S-(2R*,12Z,14E,16R*,17R*,18S*,19S*,20S*,21R*,22S*,23R*,24E)]-21-(Acetyloxy)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione; |
Article Data | 5 |
RIFAMYCIN SV Synthetic route
- 6998-60-3
rifamycin SV
| Conditions | Yield |
|---|---|
| With hydrazine hydrate In methanol for 0.25h; Ambient temperature; |
A
- 1206604-09-2
C39H52N2O12*ClH
B
- 6998-60-3
rifamycin SV
| Conditions | Yield |
|---|---|
| With hydrogenchloride; indium In tetrahydrofuran; water |
- 6998-60-3
rifamycin SV
| Conditions | Yield |
|---|---|
| With pyridine; hydroxylamine hydrochloride In methanol | 85% |
| Conditions | Yield |
|---|---|
| With acetic acid In N,N-dimethyl-formamide at 55℃; for 1.5h; Temperature; Molecular sieve; Large scale; | 84.55% |
- 6998-60-3
rifamycin SV
| Conditions | Yield |
|---|---|
| With potassium hexacyanoferrate(III) In pyridine | |
| With oxygen; magnesium chloride In water |
- 6998-60-3
rifamycin SV
| Conditions | Yield |
|---|---|
| With potassium hexacyanoferrate(III) |
- 6998-60-3
rifamycin SV
- 57375-25-4
3-Bromrifamycin S
| Conditions | Yield |
|---|---|
| With pyridinium hydrobromide perbromide In ethanol |
- 6998-60-3
rifamycin SV
- 51756-80-0
3-amino-O1,O4-didehydro-rifamycin
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: K3Fe(CN)6 / pyridine 2: NH3 / dioxane View Scheme |
- 6998-60-3
rifamycin SV
- 57375-24-3
3-Chlorrifamycin S
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: pyridinium bromide perbromide / ethanol 2: LiCl / acetone View Scheme |
- 6998-60-3
rifamycin SV
- 57375-26-5
3-cyano-O1,O4-didehydro-rifamycin
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: K3Fe(CN)6 / pyridine 2: NH4Cl / dimethylformamide View Scheme |
RIFAMYCIN SV Chemical Properties
The Molecular Weight of RIFAMYCIN SV(6998-60-3): 697.77
The Molecular Structure of RIFAMYCIN SV(6998-60-3):
EINECS: 230-273-3
Index of Refraction: 1.63
Molar Refractivity: 183.18 cm3
Molar Volume: 514.2 cm3
Polarizability: 72.61 10 -24 cm3
Surface Tension: 66.7 dyne/cm
Density: 1.35 g/cm3
Boiling Point: 917.8 °C at 760 mmHg
Flash Point: 508.9 °C
Enthalpy of Vaporization: 139.82 kJ/mol
Vapour Pressure: 0 mmHg at 25°C
Synonyms: RIFAMYCIN SV;rifamycin;rifocin;rifocyn;Rifamycin S-Na;17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-21-acetate;rifamicinesv;
RIFAMYCIN SV Toxicity Data With Reference
| 1. | pic-esc 100 ng/plate | CNREA8 Cancer Research. 43 (1983),2819. | ||
| 2. | cyt-mus-mmr 6300 mmol/L/24H-C | JTSCDR Journal of Toxicological Sciences. 5 (1980),141. | ||
| 3. | orl-mus LD50:2120 mg/kg | JJANAX Japanese Journal of Antibiotics. 23 (1970),242. | ||
| 4. | ipr-mus LD50:625 mg/kg | MEIEDD Merck Index. 10 (1983),1188. | ||
| 5. | ivn-mus LD50:550 mg/kg | JMCMAR Journal of Medicinal Chemistry. 7 (1964),596. | ||
| 6. | ice-mus LD50:5800 µg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),951. |
RIFAMYCIN SV Safety Profile
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