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| Name |
Rubidazone monohydrochloride |
EINECS | N/A |
| CAS No. | 36508-71-1 | Density | 1.54g/cm3 |
| PSA | 210.23000 | LogP | 4.13900 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C34H35 N3 O10 . Cl H | Boiling Point | °Cat760mmHg |
| Molecular Weight | 682.127 | Flash Point | °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intraperitoneal route. Human systemic effects by intravenous route: cardiovascular, blood, and gastrointestinal system effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as an antineoplastic agent. See also RUBIDAZONE. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Benzoicacid, [1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide,monohydrochloride (9CI); Benzoic acid, [1-[4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide,monohydrochloride, (2S-cis)-; NSC 164011; RP 22050 hydrochloride; Rubidazonehydrochloride; Zorubicin hydrochloride |
Rubidazone monohydrochloride Chemical Properties
IUPAC Name: N-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]benzamide hydrochloride
Synonyms: Rubidazone monohydrochloride ; N'-[(1E)-1-{(2S,4S)-4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl}ethylidene]benzohydrazide hydrochloride ; Zorubicin ; Zorubicin hydrochloride
CAS NO: 36508-71-1
Molecular Formula of Rubidazone monohydrochloride (36508-71-1) : C34H36ClN3O10
Molecular Weight of Rubidazone monohydrochloride (36508-71-1) : 682.12
Molecular Structure of Rubidazone monohydrochloride (36508-71-1) : .png)
EINECS: 253-076-4
Flash Point: 481.7 °C
Enthalpy of Vaporization: 132.91 kJ/mol
Boiling Point: 872.9 °C at 760 mmHg
Vapour Pressure: 1.44E-32 mmHg at 25°C
Rubidazone monohydrochloride Toxicity Data With Reference
| 1. | mmo-sat 20 µg/plate | EJCAAH European Journal of Cancer. 19 (1983),641. | ||
| 2. | mma-sat 4 µg/plate | EJCAAH European Journal of Cancer. 19 (1983),641. | ||
| 3. | pic-esc 700 µg/L | MUREAV Mutation Research. 77 (1980),197. | ||
| 4. | oms-hmn:lym 1 mg/L | EJCAAH European Journal of Cancer. 14 (1978),741. | ||
| 5. | ivn-hmn TDLo:48 mg/kg/21D-I:CVS,GIT,BLD | CTRRDO Cancer Treatment Reports. 62 (1978),1053. | ||
| 6. | ipr-mus LD50:28,710 µg/kg | NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 . |
Rubidazone monohydrochloride Safety Profile
Poison by intraperitoneal route. Human systemic effects by intravenous route: cardiovascular, blood, and gastrointestinal system effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as an antineoplastic agent. See also RUBIDAZONE.
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