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Ruvazone

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Name

Ruvazone

EINECS N/A
CAS No. 20228-27-7 Density 1.23g/cm3
PSA 91.48000 LogP 1.85040
Solubility N/A Melting Point 185°C
Formula C12H14 N2 O4 Boiling Point °Cat760mmHg
Molecular Weight 250.254 Flash Point °C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, subcutaneous, intramuscular, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 20228-27-7 (Ruvazone) Hazard Symbols N/A
Synonyms

Benzoicacid, 2-ethoxy-, (1-carboxyethylidene)hydrazide (9CI); Benzoic acid, o-ethoxy-,(1-carboxyethylidene)hydrazide (8CI); M 6/42; M 6/42 (pharmaceutical); Pyruvicacid o-ethoxybenzoylhydrazone; Ruvazone

 

Ruvazone Chemical Properties

 Ruvazone with CAS register number of 20228-27-7 has some synonyms as 2-Ethoxybenzoic acid 2-(1-carboxyethylidene) hydrazide ; Etossidrazone ; M6/42 ; M6-42 ; Ruvazon [INN-Spanish] ; Ruvazonum [INN-Latin] ; Pyruvic acid, O-ethoxybenzoylhydrazone ; BRN 2591488 ; o-Ethoxy-benzoyl-hydrazone of pyruvic acid ; CID9570360 ,and so on.
IUPAC Name: (2E)-2-[(2-ethoxybenzoyl)hydrazinylidene]propanoic acid
CAS: 20228-27-7
Molecular Formula: C12H14N2O4
Molecular Weight: 250.2506
Molecular structure:
ACD/LogD (pH 5.5):  -3 
ACD/LogD (pH 7.4):  -3 
ACD/BCF (pH 5.5):  1 
ACD/BCF (pH 7.4):  1 
ACD/KOC (pH 5.5):  1 
ACD/KOC (pH 7.4):  1 
H bond acceptors:  6 
H bond donors:  2 
Freely Rotating Bonds:  5 
Index of Refraction:  1.552 
Molar Refractivity:  64.982 cm3 
Molar Volume:  203.35 cm3 
Polarizability:  25.761×10-24cm3 
Surface Tension:  43.933 dyne/cm 
Density:  1.231 g/cm3 

Ruvazone Uses

 Ruvazone (CAS No.20228-27-7) is mainly used as chemical reagent.

Ruvazone Toxicity Data With Reference

1.    

orl-rat LD50:507 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.
2.    

ipr-rat LD50:157 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.
3.    

scu-rat LD50:600 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.
4.    

ims-rat LD50:206 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.
5.    

orl-mus LD50:324 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.
6.    

ipr-mus LD50:166 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.
7.    

scu-mus LD50:207 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.
8.    

ims-mus LD50:185 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 107 (1968),769.

Ruvazone Safety Profile

 Ruvazone (CAS No.20228-27-7) is poisonous by ingestion, subcutaneous, intramuscular, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

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